Recent advances in the diagnosis of benign prostatic hyperplasia

Benign Prostatic Hyperplasia (BPH) is a progressive disease, which is present in more than 50% of men over 50 years of age. The development of this pathology involves prostatic cellular growth in the glandular area that surrounds the proximal urethra, namely transitional zone. Therefore, this gross...

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Autores principales: González Calvar, S.I., Salcedo, J.L., Martínez Mangini, M.Á.
Formato: JOUR
Materias:
Androgen
Benign prostatic hyperplasia
Estrogen
Growth factors
Prolactin
Prostate
Specific prostatic antigen
Transforming growth factor-β
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03252957_v39_n2_p171_GonzalezCalvar
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03252957_v39_n2_p171_GonzalezCalvar
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spelling todo:paper_03252957_v39_n2_p171_GonzalezCalvar2023-10-03T15:23:37Z Recent advances in the diagnosis of benign prostatic hyperplasia González Calvar, S.I. Salcedo, J.L. Martínez Mangini, M.Á. Androgen Benign prostatic hyperplasia Estrogen Growth factors Prolactin Prostate Specific prostatic antigen Transforming growth factor-β Benign Prostatic Hyperplasia (BPH) is a progressive disease, which is present in more than 50% of men over 50 years of age. The development of this pathology involves prostatic cellular growth in the glandular area that surrounds the proximal urethra, namely transitional zone. Therefore, this gross glandular enlargement causes urinary retention, renal disfunction and infection. Every aging man affected by BPH needs a precise diagnosis of the disease in order to apply the proper treatment and ameliorate the symptoms that affect their quality of life. Epidemiological studies are made to gain more insight into the interrelationships among different factors participating in the etiology and pathogenesis of a disease and, furthermore to elaborate a rational approach on its early diagnosis. Particularly, the interpretation of epidemiological studies in BPH is difficult since no reliable tools exist that would clearly identify this pathology. In this context, it is important to search for a valuable biochemical marker for the precise diagnosis of BPH. This review will analyze the main factors that participate in the regulation of prostatic growth and that might influence on the pathogenesis of BPH. Consequently, it will evaluate the different parameters used in the early diagnosis of the disease. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03252957_v39_n2_p171_GonzalezCalvar
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Androgen
Benign prostatic hyperplasia
Estrogen
Growth factors
Prolactin
Prostate
Specific prostatic antigen
Transforming growth factor-β
spellingShingle Androgen
Benign prostatic hyperplasia
Estrogen
Growth factors
Prolactin
Prostate
Specific prostatic antigen
Transforming growth factor-β
González Calvar, S.I.
Salcedo, J.L.
Martínez Mangini, M.Á.
Recent advances in the diagnosis of benign prostatic hyperplasia
topic_facet Androgen
Benign prostatic hyperplasia
Estrogen
Growth factors
Prolactin
Prostate
Specific prostatic antigen
Transforming growth factor-β
description Benign Prostatic Hyperplasia (BPH) is a progressive disease, which is present in more than 50% of men over 50 years of age. The development of this pathology involves prostatic cellular growth in the glandular area that surrounds the proximal urethra, namely transitional zone. Therefore, this gross glandular enlargement causes urinary retention, renal disfunction and infection. Every aging man affected by BPH needs a precise diagnosis of the disease in order to apply the proper treatment and ameliorate the symptoms that affect their quality of life. Epidemiological studies are made to gain more insight into the interrelationships among different factors participating in the etiology and pathogenesis of a disease and, furthermore to elaborate a rational approach on its early diagnosis. Particularly, the interpretation of epidemiological studies in BPH is difficult since no reliable tools exist that would clearly identify this pathology. In this context, it is important to search for a valuable biochemical marker for the precise diagnosis of BPH. This review will analyze the main factors that participate in the regulation of prostatic growth and that might influence on the pathogenesis of BPH. Consequently, it will evaluate the different parameters used in the early diagnosis of the disease.
format JOUR
author González Calvar, S.I.
Salcedo, J.L.
Martínez Mangini, M.Á.
author_facet González Calvar, S.I.
Salcedo, J.L.
Martínez Mangini, M.Á.
author_sort González Calvar, S.I.
title Recent advances in the diagnosis of benign prostatic hyperplasia
title_short Recent advances in the diagnosis of benign prostatic hyperplasia
title_full Recent advances in the diagnosis of benign prostatic hyperplasia
title_fullStr Recent advances in the diagnosis of benign prostatic hyperplasia
title_full_unstemmed Recent advances in the diagnosis of benign prostatic hyperplasia
title_sort recent advances in the diagnosis of benign prostatic hyperplasia
url http://hdl.handle.net/20.500.12110/paper_03252957_v39_n2_p171_GonzalezCalvar
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AT salcedojl recentadvancesinthediagnosisofbenignprostatichyperplasia
AT martinezmanginima recentadvancesinthediagnosisofbenignprostatichyperplasia
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