Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans

Incubation of Candida albicans yeast cells with human luteinizing hormone (hLH), human chorionic gonadotrophin (hCG) or glucagon produced a significant rise in cAMP total levels. The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+, GTP-dependent...

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Autores principales: Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S.
Formato: JOUR
Materias:
adenylate cyclase
chorionic gonadotropin
cyclic amp
glucagon
luteinizing hormone
article
candida albicans
nonhuman
priority journal
steroidogenesis
Adenylate Cyclase
Candida albicans
Cell Membrane Permeability
Chorionic Gonadotropin
Cyclic AMP
Glucagon
Human
Luteinizing Hormone
Magnesium
Protein Kinases
Second Messenger Systems
Support, Non-U.S. Gov't
Toluene
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03091651_v15_n2_p169_Paveto
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03091651_v15_n2_p169_Paveto
record_format dspace
spelling todo:paper_03091651_v15_n2_p169_Paveto2023-10-03T15:23:00Z Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans Paveto, C. Mallo, G. Egidy, G. Galvagno, M.A. Passeron, S. adenylate cyclase chorionic gonadotropin cyclic amp glucagon luteinizing hormone article candida albicans nonhuman priority journal steroidogenesis Adenylate Cyclase Candida albicans Cell Membrane Permeability Chorionic Gonadotropin Cyclic AMP Glucagon Human Luteinizing Hormone Magnesium Protein Kinases Second Messenger Systems Support, Non-U.S. Gov't Toluene Incubation of Candida albicans yeast cells with human luteinizing hormone (hLH), human chorionic gonadotrophin (hCG) or glucagon produced a significant rise in cAMP total levels. The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+, GTP-dependent adenylyl cyclase activity as well as full activation of the cAMP-dependent protein kinase (PKA) activity. These results indicate that the interaction of the mammalian hormones with the fungus triggered the cAMP activation cascade in a similar way to that found in higher eukaryotic organisms. © 1991. Fil:Paveto, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mallo, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Egidy, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Galvagno, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03091651_v15_n2_p169_Paveto
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic adenylate cyclase
chorionic gonadotropin
cyclic amp
glucagon
luteinizing hormone
article
candida albicans
nonhuman
priority journal
steroidogenesis
Adenylate Cyclase
Candida albicans
Cell Membrane Permeability
Chorionic Gonadotropin
Cyclic AMP
Glucagon
Human
Luteinizing Hormone
Magnesium
Protein Kinases
Second Messenger Systems
Support, Non-U.S. Gov't
Toluene
spellingShingle adenylate cyclase
chorionic gonadotropin
cyclic amp
glucagon
luteinizing hormone
article
candida albicans
nonhuman
priority journal
steroidogenesis
Adenylate Cyclase
Candida albicans
Cell Membrane Permeability
Chorionic Gonadotropin
Cyclic AMP
Glucagon
Human
Luteinizing Hormone
Magnesium
Protein Kinases
Second Messenger Systems
Support, Non-U.S. Gov't
Toluene
Paveto, C.
Mallo, G.
Egidy, G.
Galvagno, M.A.
Passeron, S.
Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
topic_facet adenylate cyclase
chorionic gonadotropin
cyclic amp
glucagon
luteinizing hormone
article
candida albicans
nonhuman
priority journal
steroidogenesis
Adenylate Cyclase
Candida albicans
Cell Membrane Permeability
Chorionic Gonadotropin
Cyclic AMP
Glucagon
Human
Luteinizing Hormone
Magnesium
Protein Kinases
Second Messenger Systems
Support, Non-U.S. Gov't
Toluene
description Incubation of Candida albicans yeast cells with human luteinizing hormone (hLH), human chorionic gonadotrophin (hCG) or glucagon produced a significant rise in cAMP total levels. The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+, GTP-dependent adenylyl cyclase activity as well as full activation of the cAMP-dependent protein kinase (PKA) activity. These results indicate that the interaction of the mammalian hormones with the fungus triggered the cAMP activation cascade in a similar way to that found in higher eukaryotic organisms. © 1991.
format JOUR
author Paveto, C.
Mallo, G.
Egidy, G.
Galvagno, M.A.
Passeron, S.
author_facet Paveto, C.
Mallo, G.
Egidy, G.
Galvagno, M.A.
Passeron, S.
author_sort Paveto, C.
title Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
title_short Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
title_full Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
title_fullStr Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
title_full_unstemmed Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
title_sort activation of the camp cascade by steroidogenic hormones and glucagon in the pathogenic fungus candida albicans
url http://hdl.handle.net/20.500.12110/paper_03091651_v15_n2_p169_Paveto
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AT mallog activationofthecampcascadebysteroidogenichormonesandglucagoninthepathogenicfunguscandidaalbicans
AT egidyg activationofthecampcascadebysteroidogenichormonesandglucagoninthepathogenicfunguscandidaalbicans
AT galvagnoma activationofthecampcascadebysteroidogenichormonesandglucagoninthepathogenicfunguscandidaalbicans
AT passerons activationofthecampcascadebysteroidogenichormonesandglucagoninthepathogenicfunguscandidaalbicans
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