Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary

1. 1. Ovine luteinizing hormone (LH) stimulates cyclic AMP (cAMP) and progeterone production (P) throughout late ontogeny of the chick ovary and cAMP mimicks LH in stimulating P secretion but: 2. 2. P/cAMP ratios are lower at the earliest stages than at hatching, LH enhancing this tendency. 3. 3. Im...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: González, C.B., Cantore, M.L., Lantos, C.P., Passeron, S.
Formato: JOUR
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03050491_v96_n1_p53_Gonzalez
Aporte de:
id todo:paper_03050491_v96_n1_p53_Gonzalez
record_format dspace
spelling todo:paper_03050491_v96_n1_p53_Gonzalez2023-10-03T15:21:22Z Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary González, C.B. Cantore, M.L. Lantos, C.P. Passeron, S. cyclic amp luteinizing hormone progesterone radioisotope animal cell article chicken nonhuman ovary priority journal Animal Bucladesine Chick Embryo Cyclic AMP Female Forskolin Luteinizing Hormone Ovary Progesterone Second Messenger Systems Steroids Support, Non-U.S. Gov't Animalia Gallus gallus Ovis 1. 1. Ovine luteinizing hormone (LH) stimulates cyclic AMP (cAMP) and progeterone production (P) throughout late ontogeny of the chick ovary and cAMP mimicks LH in stimulating P secretion but: 2. 2. P/cAMP ratios are lower at the earliest stages than at hatching, LH enhancing this tendency. 3. 3. Immediately before hatching, on day 19 time-courses of LH stimulations of cAMP and P are different. 4. (4) cAMP and P respond differently to increasing doses of LH but similarly to increasing doses of forskolin. 5. (5) 1.5 mM dibutyryl cAMP (I) and 100 ng LH (II) increase P maximally, 2.5- and 3.3-fold respectively, but a mixture (I + II) increases P 7.5-fold. © 1990. Fil:González, C.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cantore, M.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03050491_v96_n1_p53_Gonzalez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic cyclic amp
luteinizing hormone
progesterone
radioisotope
animal cell
article
chicken
nonhuman
ovary
priority journal
Animal
Bucladesine
Chick Embryo
Cyclic AMP
Female
Forskolin
Luteinizing Hormone
Ovary
Progesterone
Second Messenger Systems
Steroids
Support, Non-U.S. Gov't
Animalia
Gallus gallus
Ovis
spellingShingle cyclic amp
luteinizing hormone
progesterone
radioisotope
animal cell
article
chicken
nonhuman
ovary
priority journal
Animal
Bucladesine
Chick Embryo
Cyclic AMP
Female
Forskolin
Luteinizing Hormone
Ovary
Progesterone
Second Messenger Systems
Steroids
Support, Non-U.S. Gov't
Animalia
Gallus gallus
Ovis
González, C.B.
Cantore, M.L.
Lantos, C.P.
Passeron, S.
Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
topic_facet cyclic amp
luteinizing hormone
progesterone
radioisotope
animal cell
article
chicken
nonhuman
ovary
priority journal
Animal
Bucladesine
Chick Embryo
Cyclic AMP
Female
Forskolin
Luteinizing Hormone
Ovary
Progesterone
Second Messenger Systems
Steroids
Support, Non-U.S. Gov't
Animalia
Gallus gallus
Ovis
description 1. 1. Ovine luteinizing hormone (LH) stimulates cyclic AMP (cAMP) and progeterone production (P) throughout late ontogeny of the chick ovary and cAMP mimicks LH in stimulating P secretion but: 2. 2. P/cAMP ratios are lower at the earliest stages than at hatching, LH enhancing this tendency. 3. 3. Immediately before hatching, on day 19 time-courses of LH stimulations of cAMP and P are different. 4. (4) cAMP and P respond differently to increasing doses of LH but similarly to increasing doses of forskolin. 5. (5) 1.5 mM dibutyryl cAMP (I) and 100 ng LH (II) increase P maximally, 2.5- and 3.3-fold respectively, but a mixture (I + II) increases P 7.5-fold. © 1990.
format JOUR
author González, C.B.
Cantore, M.L.
Lantos, C.P.
Passeron, S.
author_facet González, C.B.
Cantore, M.L.
Lantos, C.P.
Passeron, S.
author_sort González, C.B.
title Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
title_short Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
title_full Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
title_fullStr Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
title_full_unstemmed Cyclic AMP as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
title_sort cyclic amp as an intracellular messenger of gonadotrophin-induced steroidogenesis during the development of the embryonic chick ovary
url http://hdl.handle.net/20.500.12110/paper_03050491_v96_n1_p53_Gonzalez
work_keys_str_mv AT gonzalezcb cyclicampasanintracellularmessengerofgonadotrophininducedsteroidogenesisduringthedevelopmentoftheembryonicchickovary
AT cantoreml cyclicampasanintracellularmessengerofgonadotrophininducedsteroidogenesisduringthedevelopmentoftheembryonicchickovary
AT lantoscp cyclicampasanintracellularmessengerofgonadotrophininducedsteroidogenesisduringthedevelopmentoftheembryonicchickovary
AT passerons cyclicampasanintracellularmessengerofgonadotrophininducedsteroidogenesisduringthedevelopmentoftheembryonicchickovary
_version_ 1807320264538587136