P19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation

Background During evolution, organisms with renewable tissues have developed mechanisms to prevent tumorigenesis, including cellular senescence and apoptosis. Cellular senescence is characterized by a permanent cell cycle arrest triggered by both endogenous stress and exogenous stress. The p19INK4d,...

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Detalles Bibliográficos
Autores principales:	Sonzogni, S.V., Ogara, M.F., Belluscio, L.M., Castillo, D.S., Scassa, M.E., Cánepa, E.T.
Formato:	JOUR
Materias:	Aging CDK inhibitor Cellular senescence DNA damage Heterochromatin beta galactosidase cyclin dependent kinase inhibitor 2D messenger RNA protein p16 protein p21 aged animal cell animal tissue article BHK cell line cell aging cell cycle arrest cell nucleus cellular distribution chromatin condensation controlled study HEK293 cell line heterochromatin human human cell male mouse nonhuman priority journal promoter region protein expression protein localization signal transduction tissue distribution transcription initiation upregulation Animals beta-Galactosidase Carcinogenesis Cell Aging Cell Cycle Checkpoints Cyclin-Dependent Kinase Inhibitor p19 DNA Damage Gene Expression Regulation Mice
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03044165_v1840_n7_p2171_Sonzogni
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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