Experimental cystic echinococcosis therapy: In vitro and in vivo combined 5-fluorouracil/albendazole treatment

Human cystic echinococcosis is a zoonosis caused by the larval stage of the tapeworm Echinococcus granulosus sensu lato (s. l.). Although benzimidazole compounds such as albendazole (ABZ) and mebendazole have been the cornerstone of chemotherapy for the disease, there is often no complete recovery a...

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Detalles Bibliográficos
Autores principales: Pensel, P.E., Elissondo, N., Gambino, G., Gamboa, G.U., Benoit, J.P., Elissondo, M.C.
Formato: JOUR
Materias:
5-fluorouracil
Albendazole
Cystic echinococcosis
Echinococcus granulosus sensu stricto
albendazole
fluorouracil
animal experiment
animal model
Article
concentration response
controlled study
drug efficacy
echinococcosis
Echinococcus granulosus
experimental infection
female
in vitro study
in vivo study
larval stage
metacestode
monotherapy
mouse
nonhuman
parasite viability
scanning electron microscopy
suspension
treatment response
ultrastructure
animal
combination drug therapy
dose response
Animals
Dose-Response Relationship, Drug
Drug Therapy, Combination
Echinococcosis
Female
Fluorouracil
Mice
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03044017_v245_n_p62_Pensel
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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