Role of 3'-5'-cyclic adenosine monophosphate on the epidermal growth factor dependent survival in mammary epithelial cells

Epidermal growth factor (EGF) has been suggested to play a key role in the maintenance of epithelial cell survival during lactation. Previously, we demonstrated that EGF dependent activation of PI3K pathway prevents apoptosis in confluent murine HC11 cells cultured under low nutrient conditions. The...

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Detalles Bibliográficos
Autores principales: Grinman, D.Y., Romorini, L., Presman, D.M., Rocha-Viegas, L., Coso, O.A., Davio, C., Pecci, A.
Formato: JOUR
Materias:
Apoptosis
Bcl-X
CAMP
CREB
EGF
Mammary epithelial cells
3' 5' cyclic adenosine monophosphate
adenosine phosphate
adenylate cyclase
cyclic AMP responsive element binding protein
epidermal growth factor
phosphatidylinositol 3 kinase
protein bcl x
protein bcl xl
protein kinase B
unclassified drug
Bcl2l1 protein, mouse
Creb1 protein, mouse
culture medium
cyclic AMP
animal cell
apoptosis
Article
breast epithelium cell
cell death
cell survival
cell viability
controlled study
correlational study
enzyme activation
mouse
nonhuman
priority journal
promoter region
protein expression
protein function
protein protein interaction
signal transduction
upregulation
animal
cell culture technique
cell line
chemistry
cytology
drug effects
female
genetics
metabolism
pharmacology
udder
Animals
bcl-X Protein
Cell Culture Techniques
Cell Line
Cell Survival
Culture Media
Cyclic AMP
Cyclic AMP Response Element-Binding Protein
Epidermal Growth Factor
Female
Mammary Glands, Animal
Mice
Promoter Regions, Genetic
Signal Transduction
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v419_n_p259_Grinman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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