Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma development

Laminin is a component of the extracellular matrix (ECM) that regulates cell proliferation and hormone secretion. Here we describe the effects of laminin on prolactin secretion in normal and tumor cells and analyze laminin expression pattern during prolactinoma development. Prolactin secretion and c...

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Detalles Bibliográficos
Autores principales: Kuchenbauer, F., Theodoropoulou, M., Hopfner, U., Stalla, J., Renner, U., Tonn, J.C., Low, M.J., Arzt, E., Stalla, G.K., Páez-Pereda, M.
Formato: JOUR
Materias:
Extracellular matrix
Laminin
Pituitary neoplasm
Prolactin
dopamine 2 receptor
laminin
prolactin
animal cell
animal model
animal tissue
article
cell proliferation
controlled study
disease course
drug effect
hormone determination
human
human tissue
hyperplasia
hypophysis
hypophysis cell
male
mouse
nonhuman
priority journal
prolactin release
prolactin secreting cell
prolactin synthesis
prolactinoma
protein analysis
protein deficiency
protein determination
protein expression
protein function
protein localization
quantitative analysis
rat
tissue distribution
tumor cell
wild type
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v207_n1-2_p13_Kuchenbauer
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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