Novel medical therapies for pituitary tumors
Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from...
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todo:paper_03013073_v38_n_p158_Theodoropoulou2023-10-03T15:18:19Z Novel medical therapies for pituitary tumors Theodoropoulou, M. Labeur, M. Paez Pereda, M. Haedo, M. Perone, M.J. Renner, U. Arzt, E. Stalla, G.K. angiopeptin bim 23 a 387 bim 23 a 760 bromocriptine cabergoline dopamine receptor stimulating agent gamma interferon octreotide pasireotide quinagolide retinoic acid unclassified drug acromegaly cancer chemotherapy cancer radiotherapy cancer surgery Cushing syndrome growth hormone secreting adenoma human hypophysis tumor multimodality cancer therapy neuroendocrine tumor nonhuman priority journal prolactinoma review Dopamine Dopamine Agonists Humans Interferon-gamma Pituitary Neoplasms Somatostatin Tretinoin Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors. Copyright © 2010 S. Karger AG, Basel. Fil:Labeur, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Paez Pereda, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Haedo, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. SER info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03013073_v38_n_p158_Theodoropoulou |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
angiopeptin bim 23 a 387 bim 23 a 760 bromocriptine cabergoline dopamine receptor stimulating agent gamma interferon octreotide pasireotide quinagolide retinoic acid unclassified drug acromegaly cancer chemotherapy cancer radiotherapy cancer surgery Cushing syndrome growth hormone secreting adenoma human hypophysis tumor multimodality cancer therapy neuroendocrine tumor nonhuman priority journal prolactinoma review Dopamine Dopamine Agonists Humans Interferon-gamma Pituitary Neoplasms Somatostatin Tretinoin |
spellingShingle |
angiopeptin bim 23 a 387 bim 23 a 760 bromocriptine cabergoline dopamine receptor stimulating agent gamma interferon octreotide pasireotide quinagolide retinoic acid unclassified drug acromegaly cancer chemotherapy cancer radiotherapy cancer surgery Cushing syndrome growth hormone secreting adenoma human hypophysis tumor multimodality cancer therapy neuroendocrine tumor nonhuman priority journal prolactinoma review Dopamine Dopamine Agonists Humans Interferon-gamma Pituitary Neoplasms Somatostatin Tretinoin Theodoropoulou, M. Labeur, M. Paez Pereda, M. Haedo, M. Perone, M.J. Renner, U. Arzt, E. Stalla, G.K. Novel medical therapies for pituitary tumors |
topic_facet |
angiopeptin bim 23 a 387 bim 23 a 760 bromocriptine cabergoline dopamine receptor stimulating agent gamma interferon octreotide pasireotide quinagolide retinoic acid unclassified drug acromegaly cancer chemotherapy cancer radiotherapy cancer surgery Cushing syndrome growth hormone secreting adenoma human hypophysis tumor multimodality cancer therapy neuroendocrine tumor nonhuman priority journal prolactinoma review Dopamine Dopamine Agonists Humans Interferon-gamma Pituitary Neoplasms Somatostatin Tretinoin |
description |
Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors. Copyright © 2010 S. Karger AG, Basel. |
format |
SER |
author |
Theodoropoulou, M. Labeur, M. Paez Pereda, M. Haedo, M. Perone, M.J. Renner, U. Arzt, E. Stalla, G.K. |
author_facet |
Theodoropoulou, M. Labeur, M. Paez Pereda, M. Haedo, M. Perone, M.J. Renner, U. Arzt, E. Stalla, G.K. |
author_sort |
Theodoropoulou, M. |
title |
Novel medical therapies for pituitary tumors |
title_short |
Novel medical therapies for pituitary tumors |
title_full |
Novel medical therapies for pituitary tumors |
title_fullStr |
Novel medical therapies for pituitary tumors |
title_full_unstemmed |
Novel medical therapies for pituitary tumors |
title_sort |
novel medical therapies for pituitary tumors |
url |
http://hdl.handle.net/20.500.12110/paper_03013073_v38_n_p158_Theodoropoulou |
work_keys_str_mv |
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1782030544011264000 |