Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum

1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/k...

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Autores principales:	Reboreda, J.C., Segura, E.T.
Formato:	JOUR
Materias:	angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_03009629_v93_n3_p505_Reboreda2023-10-03T15:18:10Z Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum Reboreda, J.C. Segura, E.T. angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis 1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/kg). 3. 3. In a similar way, single intracerebroventricular injections of 1 μl 10-4M angiotensin II, decreased urine production but did not affect water uptake. 4. 4. Finally, systemic injections of the angiotensin blocker salarasin (100 μg/kg) did not affect the cutaneous hydrosmotic response of dehydrated toads. 5. 5. We conclude that angiotensin II has no effects on water uptake in this species. The antidiuretic response to angiotensin II, and the involvement of adrenergic mechanisms are discussed. © 1989. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis
spellingShingle	angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis Reboreda, J.C. Segura, E.T. Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
topic_facet	angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis
description	1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/kg). 3. 3. In a similar way, single intracerebroventricular injections of 1 μl 10-4M angiotensin II, decreased urine production but did not affect water uptake. 4. 4. Finally, systemic injections of the angiotensin blocker salarasin (100 μg/kg) did not affect the cutaneous hydrosmotic response of dehydrated toads. 5. 5. We conclude that angiotensin II has no effects on water uptake in this species. The antidiuretic response to angiotensin II, and the involvement of adrenergic mechanisms are discussed. © 1989.
format	JOUR
author	Reboreda, J.C. Segura, E.T.
author_facet	Reboreda, J.C. Segura, E.T.
author_sort	Reboreda, J.C.
title	Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
title_short	Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
title_full	Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
title_fullStr	Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
title_full_unstemmed	Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
title_sort	water balance effects of systemic and intracerebroventricular administration of angiotensin ii in the toad bufo arenarum
url	http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda
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Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum

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