Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyp...
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todo:paper_03008177_v31_n2_p97_GarciaPatrone2023-10-03T15:17:46Z Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US Garcia-Patrone, M. animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyphenylalanine synthesis shown by stationary phase ribosomes. Association factor I is able to bind to free 30S-50S ribosomal couples but not to polysomes, and exerts its effect by inhibiting the initiation step of protein synthesis. Ribosomes preincubated with association factor I have a decreased ability for polypeptide snythesis directed phage mRNA or poly(U). © 1980 Dr. W. Junk b.v. Publishers. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03008177_v31_n2_p97_GarciaPatrone |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral |
spellingShingle |
animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral Garcia-Patrone, M. Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
topic_facet |
animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral |
description |
The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyphenylalanine synthesis shown by stationary phase ribosomes. Association factor I is able to bind to free 30S-50S ribosomal couples but not to polysomes, and exerts its effect by inhibiting the initiation step of protein synthesis. Ribosomes preincubated with association factor I have a decreased ability for polypeptide snythesis directed phage mRNA or poly(U). © 1980 Dr. W. Junk b.v. Publishers. |
format |
JOUR |
author |
Garcia-Patrone, M. |
author_facet |
Garcia-Patrone, M. |
author_sort |
Garcia-Patrone, M. |
title |
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
title_short |
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
title_full |
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
title_fullStr |
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
title_full_unstemmed |
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US |
title_sort |
mechanism of protein synthesis inhibition during stationary phase in bacillus stearothermophil us |
url |
http://hdl.handle.net/20.500.12110/paper_03008177_v31_n2_p97_GarciaPatrone |
work_keys_str_mv |
AT garciapatronem mechanismofproteinsynthesisinhibitionduringstationaryphaseinbacillusstearothermophilus |
_version_ |
1782026937509609472 |