Probing consciousness in a sensory-disconnected paralyzed patient
Background: Diagnosis of consciousness can be very challenging in some clinical situations such as severe sensory-motor impairments. Case study: We report the case study of a patient who presented a total “locked-in syndrome” associated with and a multi-sensory deafferentation (visual, auditory and...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_02699052_v31_n10_p1398_Rohaut |
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todo:paper_02699052_v31_n10_p1398_Rohaut2023-10-03T15:14:23Z Probing consciousness in a sensory-disconnected paralyzed patient Rohaut, B. Raimondo, F. Galanaud, D. Valente, M. Sitt, J.D. Naccache, L. brain functional imagery consciousness disorder of consciousness locked-in syndrome quantitative EEG abdominal surgery acute disease adult Article atherosclerosis basilar artery obstruction brain stem infarction case report chronic kidney failure clinical article colitis consciousness coughing deafferentation dyslipidemia electroencephalogram hartmann procedure heart arrhythmia human hypertension kidney transplantation locked in syndrome male middle aged neurologic examination nociceptive stimulation nuclear magnetic resonance imaging pupil reflex sedation septic shock startle reflex vegetative stage wakefulness brain consciousness disorder electroencephalography functional neuroimaging pathophysiology quadriplegia Brain Consciousness Disorders Electroencephalography Functional Neuroimaging Humans Male Middle Aged Quadriplegia Background: Diagnosis of consciousness can be very challenging in some clinical situations such as severe sensory-motor impairments. Case study: We report the case study of a patient who presented a total “locked-in syndrome” associated with and a multi-sensory deafferentation (visual, auditory and tactile modalities) following a protuberantial infarction. Result: In spite of this severe and extreme disconnection from the external world, we could detect reliable evidence of consciousness using a multivariate analysis of his high-density resting state electroencephalogram. This EEG-based diagnosis was eventually confirmed by the clinical evolution of the patient. Conclusion: This approach illustrates the potential importance of functional brain-imaging data to improve diagnosis of consciousness and of cognitive abilities in critical situations in which the behavioral channel is compromised such as deafferented locked-in syndrome. © 2017 Taylor & Francis Group, LLC. Fil:Sitt, J.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_02699052_v31_n10_p1398_Rohaut |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
brain functional imagery consciousness disorder of consciousness locked-in syndrome quantitative EEG abdominal surgery acute disease adult Article atherosclerosis basilar artery obstruction brain stem infarction case report chronic kidney failure clinical article colitis consciousness coughing deafferentation dyslipidemia electroencephalogram hartmann procedure heart arrhythmia human hypertension kidney transplantation locked in syndrome male middle aged neurologic examination nociceptive stimulation nuclear magnetic resonance imaging pupil reflex sedation septic shock startle reflex vegetative stage wakefulness brain consciousness disorder electroencephalography functional neuroimaging pathophysiology quadriplegia Brain Consciousness Disorders Electroencephalography Functional Neuroimaging Humans Male Middle Aged Quadriplegia |
| spellingShingle |
brain functional imagery consciousness disorder of consciousness locked-in syndrome quantitative EEG abdominal surgery acute disease adult Article atherosclerosis basilar artery obstruction brain stem infarction case report chronic kidney failure clinical article colitis consciousness coughing deafferentation dyslipidemia electroencephalogram hartmann procedure heart arrhythmia human hypertension kidney transplantation locked in syndrome male middle aged neurologic examination nociceptive stimulation nuclear magnetic resonance imaging pupil reflex sedation septic shock startle reflex vegetative stage wakefulness brain consciousness disorder electroencephalography functional neuroimaging pathophysiology quadriplegia Brain Consciousness Disorders Electroencephalography Functional Neuroimaging Humans Male Middle Aged Quadriplegia Rohaut, B. Raimondo, F. Galanaud, D. Valente, M. Sitt, J.D. Naccache, L. Probing consciousness in a sensory-disconnected paralyzed patient |
| topic_facet |
brain functional imagery consciousness disorder of consciousness locked-in syndrome quantitative EEG abdominal surgery acute disease adult Article atherosclerosis basilar artery obstruction brain stem infarction case report chronic kidney failure clinical article colitis consciousness coughing deafferentation dyslipidemia electroencephalogram hartmann procedure heart arrhythmia human hypertension kidney transplantation locked in syndrome male middle aged neurologic examination nociceptive stimulation nuclear magnetic resonance imaging pupil reflex sedation septic shock startle reflex vegetative stage wakefulness brain consciousness disorder electroencephalography functional neuroimaging pathophysiology quadriplegia Brain Consciousness Disorders Electroencephalography Functional Neuroimaging Humans Male Middle Aged Quadriplegia |
| description |
Background: Diagnosis of consciousness can be very challenging in some clinical situations such as severe sensory-motor impairments. Case study: We report the case study of a patient who presented a total “locked-in syndrome” associated with and a multi-sensory deafferentation (visual, auditory and tactile modalities) following a protuberantial infarction. Result: In spite of this severe and extreme disconnection from the external world, we could detect reliable evidence of consciousness using a multivariate analysis of his high-density resting state electroencephalogram. This EEG-based diagnosis was eventually confirmed by the clinical evolution of the patient. Conclusion: This approach illustrates the potential importance of functional brain-imaging data to improve diagnosis of consciousness and of cognitive abilities in critical situations in which the behavioral channel is compromised such as deafferented locked-in syndrome. © 2017 Taylor & Francis Group, LLC. |
| format |
JOUR |
| author |
Rohaut, B. Raimondo, F. Galanaud, D. Valente, M. Sitt, J.D. Naccache, L. |
| author_facet |
Rohaut, B. Raimondo, F. Galanaud, D. Valente, M. Sitt, J.D. Naccache, L. |
| author_sort |
Rohaut, B. |
| title |
Probing consciousness in a sensory-disconnected paralyzed patient |
| title_short |
Probing consciousness in a sensory-disconnected paralyzed patient |
| title_full |
Probing consciousness in a sensory-disconnected paralyzed patient |
| title_fullStr |
Probing consciousness in a sensory-disconnected paralyzed patient |
| title_full_unstemmed |
Probing consciousness in a sensory-disconnected paralyzed patient |
| title_sort |
probing consciousness in a sensory-disconnected paralyzed patient |
| url |
http://hdl.handle.net/20.500.12110/paper_02699052_v31_n10_p1398_Rohaut |
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AT rohautb probingconsciousnessinasensorydisconnectedparalyzedpatient AT raimondof probingconsciousnessinasensorydisconnectedparalyzedpatient AT galanaudd probingconsciousnessinasensorydisconnectedparalyzedpatient AT valentem probingconsciousnessinasensorydisconnectedparalyzedpatient AT sittjd probingconsciousnessinasensorydisconnectedparalyzedpatient AT naccachel probingconsciousnessinasensorydisconnectedparalyzedpatient |
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