Expression of gelatinise/type IV collagenase in tumor necrosis correlates with cell detachment and tumor invasion

We have previously observed that acellular extracts from necrotic areas (NE) of the non-metastatic murine mammary adenocarcinoma M3, enhance in vitro cell detachment and spontaneous lung metastases. In the present study, using different proteinase inhibitors along with NE, only the calcium chelator...

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Detalles Bibliográficos
Autores principales: Daniel Bonfil, R., Medina, P.A., Gómez, D.E., Farias, E., Lazarowski, A., Gritti, M.F.L., Meiss, R.P., Bustuoabad, O.D.
Formato: JOUR
Materias:
gelatinase
metalloproteinases
tumor invasion
tumor necrosis
type IV collagenase
antibody
collagenase
edetic acid
proteinase inhibitor
animal model
article
breast adenocarcinoma
cancer invasion
cell division
cell line
controlled study
enzyme activity
female
metastasis
mouse
nonhuman
Animal
Cell Adhesion
Collagen
Extracellular Matrix
Female
Gelatinases
Mice
Mice, Inbred BALB C
Microbial Collagenase
Necrosis
Neoplasm Invasiveness
Neoplasms, Experimental
Pepsin A
Protease Inhibitors
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02620898_v10_n3_p211_DanielBonfil
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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