Glucocorticoid receptors and inhibition of serum prolactin by dexamethasone are reduced in rats with estrogen-induced pituitary tumors

In estrogen-induced pituitary tumors, binding of (3H)-dexamethasone (DEX) to soluble glucocorticoid receptors (GCR) was reduced 5-6 fold with respect to normal pituitaries. GCR in the tumors, however, bound normally to DNA-cellulose after heat-induced transformation. In control rats, serum prolactin...

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Detalles Bibliográficos
Autores principales:	Piroli, G., Grillo, C., Lux de Lantos, V., Libertun, C., De Nicola, A.F.
Formato:	JOUR
Materias:	dexamethasone glucocorticoid receptor prolactin animal experiment animal model article controlled study feedback system hypophysis tumor male nonhuman priority journal rat
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0172780X_v13_n2_p75_Piroli
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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