Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth

Galectin-8 (Gal-8), a ‘tandem-repeat’-type galectin, has been described as a modulator of cellular functions including adhesion, spreading, growth arrest, apoptosis, pathogen recognition, autophagy, and immunomodulation. We have previously shown that activated leukocyte cell adhesion molecule (ALCAM...

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Detalles Bibliográficos
Autores principales: Ferragut, F., Cagnoni, A.J., Colombo, L.L., Sánchez Terrero, C., Wolfenstein-Todel, C., Troncoso, M.F., Vanzulli, S.I., Rabinovich, G.A., Mariño, K.V., Elola, M.T.
Formato: JOUR
Materias:
ALCAM (CD166)
Cell adhesion and migration
Galectin-8
N-glycosylation
Sialylation
Triple negative breast cancer
Tumor growth
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01674889_v_n_p_Ferragut
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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