Induction of a refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L

A partially purified plant inhibitor (Meliacin) isolated from Melia azedarach L induced in cells a refractory state to virus infection. Meliacin was active in a large variety of continuous and/or primary cell cultures. A state of maximum virus resistance was achieved after 2 h of incubation and was...

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Detalles Bibliográficos
Autores principales:	Andrei, G.M., Damonte, E.B., de Torres, R.A., Coto, C.E.
Formato:	JOUR
Materias:	Antiviral state Melia azedarach L Plant antiviral dactinomycin meliacine unclassified drug cell culture chicken drug mechanism nonhuman plant plant leaf priority journal virus infection Animal Antiviral Agents Cells, Cultured Human Interferons Kinetics Plants Support, Non-U.S. Gov't Vesicular stomatitis-Indiana virus Virus Inhibitors Virus Replication
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_01663542_v9_n4_p221_Andrei
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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