Nitric oxide synthase I and VIP-activated signaling are affected in salivary glands of NOD mice

The autoimmune sialadenitis developed by non-obese diabetic (NOD) mice is considered a suitable model to study the ethiopathogenic mechanisms leading to sicca symptoms in Sjögren's syndrome (SS). Evidence supporting a neural rather than immune origin of the secretory dysfunction has been provid...

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Detalles Bibliográficos
Autores principales: Rosignoli, F., Pérez Leirós, C.
Formato: JOUR
Materias:
Autoimmune sialadenitis
Nitric oxide
NOD mice
NOS isoforms
Salivary glands
VIP signaling
amylase
nitric oxide synthase
vasoactive intestinal polypeptide
amylase release
animal experiment
animal model
animal tissue
article
controlled study
diabetes mellitus
enzyme activation
enzyme activity
enzyme release
immune system
inflammation
mouse
nervous system
nonhuman
parotid gland
pathogenesis
priority journal
protein deficiency
protein expression
protein secretion
saliva level
salivation
sialoadenitis
signal transduction
Sjoegren syndrome
submandibular gland
Age Factors
Animals
Female
Male
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Neuroimmunomodulation
Nitric Oxide
Nitric Oxide Synthase
Nitric Oxide Synthase Type I
Parasympathetic Fibers, Postganglionic
Protein Isoforms
Receptors, Muscarinic
Saliva
Salivary Glands
Signal Transduction
Sjogren's Syndrome
Vasoactive Intestinal Peptide
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01655728_v130_n1-2_p109_Rosignoli
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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