Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats

The effect of superior cervical ganglionectomy (SCGx) or pinealectomy (Px) on drinking behavior was examined in rats subjected to a restricted photoperiod (i.e. 4 h of light per day). Both in male and female rats SCGx depressed water intake significantly from 1 to 3 days after surgery. After osmolar...

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Autores principales: Gejman, P.V., Cardinali, D.P., Finkielman, S., Nahmod, V.E.
Formato: JOUR
Materias:
drinking behavior
pineal gland
stress responses
superior cervical ganglia
isoprenaline
animal experiment
autonomic nervous system
central nervous system
drinking
endocrine system
intraperitoneal drug administration
pinealectomy
rat
subcutaneous drug administration
superior cervical ganglionectomy
Animal
Drinking Behavior
Female
Ganglia, Sympathetic
Isoproterenol
Male
Pineal Gland
Rats
Rats, Inbred Strains
Sodium Chloride
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01651838_v4_n3_p249_Gejman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_01651838_v4_n3_p249_Gejman
record_format dspace
spelling todo:paper_01651838_v4_n3_p249_Gejman2023-10-03T15:02:51Z Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats Gejman, P.V. Cardinali, D.P. Finkielman, S. Nahmod, V.E. drinking behavior pineal gland stress responses superior cervical ganglia isoprenaline animal experiment autonomic nervous system central nervous system drinking endocrine system intraperitoneal drug administration pinealectomy rat subcutaneous drug administration superior cervical ganglionectomy Animal Drinking Behavior Female Ganglia, Sympathetic Isoproterenol Male Pineal Gland Rats Rats, Inbred Strains Sodium Chloride The effect of superior cervical ganglionectomy (SCGx) or pinealectomy (Px) on drinking behavior was examined in rats subjected to a restricted photoperiod (i.e. 4 h of light per day). Both in male and female rats SCGx depressed water intake significantly from 1 to 3 days after surgery. After osmolar (i.p. 5% NaCl) or non-osmolar stimuli (s.c. isoproterenol) SCGx female rats exhibited a depressed response in water and NaCl intake, an effect not observed in male rats. Castration of male or female rats did not change their drinking behavior response to thirst stimuli. Px did not mimic SCGx in its effects on drinking behavior; moreover in sham-Px rats the water intake fell significantly after craniotomy. Following the injection of isoproterenol or i.p. hypertonic saline, the drinking behavior was the same in Px or sham-Px animals. To assess whether the effects of SCGx needed the presence of the pineal gland, Px or sham-Px rats were subjected to SCGx 9 days later. In both groups SCGx depressed water intake; however the inhibition that followed ganglia removal in Px rats was greater than that observed in animals with a pineal gland. Water and NaCl intake following isoproterenol or i.p. hypertonic saline were similar in both experimental groups. These results suggest that SCGx affects drinking behavior in part by pathways other than pineal denervation. © 1981. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01651838_v4_n3_p249_Gejman
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic drinking behavior
pineal gland
stress responses
superior cervical ganglia
isoprenaline
animal experiment
autonomic nervous system
central nervous system
drinking
endocrine system
intraperitoneal drug administration
pinealectomy
rat
subcutaneous drug administration
superior cervical ganglionectomy
Animal
Drinking Behavior
Female
Ganglia, Sympathetic
Isoproterenol
Male
Pineal Gland
Rats
Rats, Inbred Strains
Sodium Chloride
spellingShingle drinking behavior
pineal gland
stress responses
superior cervical ganglia
isoprenaline
animal experiment
autonomic nervous system
central nervous system
drinking
endocrine system
intraperitoneal drug administration
pinealectomy
rat
subcutaneous drug administration
superior cervical ganglionectomy
Animal
Drinking Behavior
Female
Ganglia, Sympathetic
Isoproterenol
Male
Pineal Gland
Rats
Rats, Inbred Strains
Sodium Chloride
Gejman, P.V.
Cardinali, D.P.
Finkielman, S.
Nahmod, V.E.
Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
topic_facet drinking behavior
pineal gland
stress responses
superior cervical ganglia
isoprenaline
animal experiment
autonomic nervous system
central nervous system
drinking
endocrine system
intraperitoneal drug administration
pinealectomy
rat
subcutaneous drug administration
superior cervical ganglionectomy
Animal
Drinking Behavior
Female
Ganglia, Sympathetic
Isoproterenol
Male
Pineal Gland
Rats
Rats, Inbred Strains
Sodium Chloride
description The effect of superior cervical ganglionectomy (SCGx) or pinealectomy (Px) on drinking behavior was examined in rats subjected to a restricted photoperiod (i.e. 4 h of light per day). Both in male and female rats SCGx depressed water intake significantly from 1 to 3 days after surgery. After osmolar (i.p. 5% NaCl) or non-osmolar stimuli (s.c. isoproterenol) SCGx female rats exhibited a depressed response in water and NaCl intake, an effect not observed in male rats. Castration of male or female rats did not change their drinking behavior response to thirst stimuli. Px did not mimic SCGx in its effects on drinking behavior; moreover in sham-Px rats the water intake fell significantly after craniotomy. Following the injection of isoproterenol or i.p. hypertonic saline, the drinking behavior was the same in Px or sham-Px animals. To assess whether the effects of SCGx needed the presence of the pineal gland, Px or sham-Px rats were subjected to SCGx 9 days later. In both groups SCGx depressed water intake; however the inhibition that followed ganglia removal in Px rats was greater than that observed in animals with a pineal gland. Water and NaCl intake following isoproterenol or i.p. hypertonic saline were similar in both experimental groups. These results suggest that SCGx affects drinking behavior in part by pathways other than pineal denervation. © 1981.
format JOUR
author Gejman, P.V.
Cardinali, D.P.
Finkielman, S.
Nahmod, V.E.
author_facet Gejman, P.V.
Cardinali, D.P.
Finkielman, S.
Nahmod, V.E.
author_sort Gejman, P.V.
title Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
title_short Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
title_full Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
title_fullStr Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
title_full_unstemmed Changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
title_sort changes in drinking behavior caused by superior cervical ganglionectomy and pinealectomy in rats
url http://hdl.handle.net/20.500.12110/paper_01651838_v4_n3_p249_Gejman
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AT cardinalidp changesindrinkingbehaviorcausedbysuperiorcervicalganglionectomyandpinealectomyinrats
AT finkielmans changesindrinkingbehaviorcausedbysuperiorcervicalganglionectomyandpinealectomyinrats
AT nahmodve changesindrinkingbehaviorcausedbysuperiorcervicalganglionectomyandpinealectomyinrats
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