Testosterone regulates prostaglandin production by the rat vas deferens

Prostaglandins are present in the epididymal and prostatic portions of the isolated intact and gonadectomized rat vas deferens. The concentration of PGF-like material is higher in the castrated than in the intact male rat in both portions of the vasa deferentia. The higher amount of PGF-like materia...

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Autores principales: Borda, E., Peredo, H., del C. Agostini, M., Gimeno, M.F., Gimeno, A.L.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01614630_v7_n3_p245_Borda
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spelling todo:paper_01614630_v7_n3_p245_Borda2023-10-03T15:01:19Z Testosterone regulates prostaglandin production by the rat vas deferens Borda, E. Peredo, H. del C. Agostini, M. Gimeno, M.F. Gimeno, A.L. indometacin prostaglandin testosterone testosterone propionate animal experiment castration endocrine system male genital system rat vas deferens Animals Castration Male Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Testis Testosterone Vas Deferens Prostaglandins are present in the epididymal and prostatic portions of the isolated intact and gonadectomized rat vas deferens. The concentration of PGF-like material is higher in the castrated than in the intact male rat in both portions of the vasa deferentia. The higher amount of PGF-like material observed in the castrated rat vas deferens was significantly reduced after testosterone replacement therapy, indicating that androgens could be controlling PGF production. On the other hand, the concentration of PGE-like material was significantly higher than PGF in both portions of the vas deferens and no differences were observed in those values when comparing data from intact, castrated and testosterone-treated rats. PGF-like material is likely to be androgen dependent, whereas PGE-like material is not under that hormonal control. © 1981. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01614630_v7_n3_p245_Borda
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic indometacin
prostaglandin
testosterone
testosterone propionate
animal experiment
castration
endocrine system
male genital system
rat
vas deferens
Animals
Castration
Male
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Testis
Testosterone
Vas Deferens
spellingShingle indometacin
prostaglandin
testosterone
testosterone propionate
animal experiment
castration
endocrine system
male genital system
rat
vas deferens
Animals
Castration
Male
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Testis
Testosterone
Vas Deferens
Borda, E.
Peredo, H.
del C. Agostini, M.
Gimeno, M.F.
Gimeno, A.L.
Testosterone regulates prostaglandin production by the rat vas deferens
topic_facet indometacin
prostaglandin
testosterone
testosterone propionate
animal experiment
castration
endocrine system
male genital system
rat
vas deferens
Animals
Castration
Male
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Testis
Testosterone
Vas Deferens
description Prostaglandins are present in the epididymal and prostatic portions of the isolated intact and gonadectomized rat vas deferens. The concentration of PGF-like material is higher in the castrated than in the intact male rat in both portions of the vasa deferentia. The higher amount of PGF-like material observed in the castrated rat vas deferens was significantly reduced after testosterone replacement therapy, indicating that androgens could be controlling PGF production. On the other hand, the concentration of PGE-like material was significantly higher than PGF in both portions of the vas deferens and no differences were observed in those values when comparing data from intact, castrated and testosterone-treated rats. PGF-like material is likely to be androgen dependent, whereas PGE-like material is not under that hormonal control. © 1981.
format JOUR
author Borda, E.
Peredo, H.
del C. Agostini, M.
Gimeno, M.F.
Gimeno, A.L.
author_facet Borda, E.
Peredo, H.
del C. Agostini, M.
Gimeno, M.F.
Gimeno, A.L.
author_sort Borda, E.
title Testosterone regulates prostaglandin production by the rat vas deferens
title_short Testosterone regulates prostaglandin production by the rat vas deferens
title_full Testosterone regulates prostaglandin production by the rat vas deferens
title_fullStr Testosterone regulates prostaglandin production by the rat vas deferens
title_full_unstemmed Testosterone regulates prostaglandin production by the rat vas deferens
title_sort testosterone regulates prostaglandin production by the rat vas deferens
url http://hdl.handle.net/20.500.12110/paper_01614630_v7_n3_p245_Borda
work_keys_str_mv AT bordae testosteroneregulatesprostaglandinproductionbytheratvasdeferens
AT peredoh testosteroneregulatesprostaglandinproductionbytheratvasdeferens
AT delcagostinim testosteroneregulatesprostaglandinproductionbytheratvasdeferens
AT gimenomf testosteroneregulatesprostaglandinproductionbytheratvasdeferens
AT gimenoal testosteroneregulatesprostaglandinproductionbytheratvasdeferens
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