Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes)
The organochlorine insecticide endosulfan (ES) is widely used despite its high toxicity to fish (96-h LC50 median value of 2.6γgL-1). This study aimed to assess the acute toxicity, histological and physiological parameters after exposure to 0; 0.25; 1; 2; 3; 4 and 16γgL-1 ES for 96h under semi-stati...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_01476513_v74_n4_p1065_DaCuna |
| Aporte de: |
| id |
todo:paper_01476513_v74_n4_p1065_DaCuna |
|---|---|
| record_format |
dspace |
| spelling |
todo:paper_01476513_v74_n4_p1065_DaCuna2023-10-03T15:00:45Z Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) Da Cuña, R.H. Rey Vázquez, G. Piol, M.N. Guerrero, N.V. Maggese, M.C. Lo Nostro, F.L. Acetylcholinesterase Acute toxicity Cichlid fish Endosulfan Hematology Histopathology Organochlorine pesticides Teleostei acetylcholinesterase endosulfan cichlid ecotoxicology endosulfan enzyme activity hematology histology histopathology inhibition organochlorine physiology pollution exposure toxicity test acute toxicity anemia animal tissue article Cichlasoma dimerus controlled study environmental exposure enzyme activity female freshwater species histopathology hyperplasia hypertrophy male mean corpuscular hemoglobin mean corpuscular volume mucous cell neurotoxicity nonhuman Perciformes testis injury Animals Cichlids Endosulfan Female Fresh Water Gills Hepatocytes Hydrocarbons, Chlorinated Insecticides Lethal Dose 50 Liver Male Ovary Spleen Testis Water Pollutants, Chemical Cichlasoma Cichlidae Perciformes Teleostei The organochlorine insecticide endosulfan (ES) is widely used despite its high toxicity to fish (96-h LC50 median value of 2.6γgL-1). This study aimed to assess the acute toxicity, histological and physiological parameters after exposure to 0; 0.25; 1; 2; 3; 4 and 16γgL-1 ES for 96h under semi-static conditions in a freshwater perciform fish, Cichlasoma dimerus. Prior to death, fish exhibited behavior indicative of neurotoxicity. No difference was found in brain AChE activity. A decrease in erythrocyte mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration in exposed fish suggests a state of anemia. Histological alterations observed in exposed fish included hyperplasia of the interlamellar epithelium, blood congestion in secondary lamellae, and mucous cells hyperplasia and hypertrophy in gills; pycnotic nuclei and hydropic degeneration in liver; testicular damage. These moderate pathological responses in major organs could become crucial during reproduction and under prolonged exposure periods. © 2011 Elsevier Inc. Fil:Da Cuña, R.H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rey Vázquez, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Piol, M.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Maggese, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Lo Nostro, F.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01476513_v74_n4_p1065_DaCuna |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Acetylcholinesterase Acute toxicity Cichlid fish Endosulfan Hematology Histopathology Organochlorine pesticides Teleostei acetylcholinesterase endosulfan cichlid ecotoxicology endosulfan enzyme activity hematology histology histopathology inhibition organochlorine physiology pollution exposure toxicity test acute toxicity anemia animal tissue article Cichlasoma dimerus controlled study environmental exposure enzyme activity female freshwater species histopathology hyperplasia hypertrophy male mean corpuscular hemoglobin mean corpuscular volume mucous cell neurotoxicity nonhuman Perciformes testis injury Animals Cichlids Endosulfan Female Fresh Water Gills Hepatocytes Hydrocarbons, Chlorinated Insecticides Lethal Dose 50 Liver Male Ovary Spleen Testis Water Pollutants, Chemical Cichlasoma Cichlidae Perciformes Teleostei |
| spellingShingle |
Acetylcholinesterase Acute toxicity Cichlid fish Endosulfan Hematology Histopathology Organochlorine pesticides Teleostei acetylcholinesterase endosulfan cichlid ecotoxicology endosulfan enzyme activity hematology histology histopathology inhibition organochlorine physiology pollution exposure toxicity test acute toxicity anemia animal tissue article Cichlasoma dimerus controlled study environmental exposure enzyme activity female freshwater species histopathology hyperplasia hypertrophy male mean corpuscular hemoglobin mean corpuscular volume mucous cell neurotoxicity nonhuman Perciformes testis injury Animals Cichlids Endosulfan Female Fresh Water Gills Hepatocytes Hydrocarbons, Chlorinated Insecticides Lethal Dose 50 Liver Male Ovary Spleen Testis Water Pollutants, Chemical Cichlasoma Cichlidae Perciformes Teleostei Da Cuña, R.H. Rey Vázquez, G. Piol, M.N. Guerrero, N.V. Maggese, M.C. Lo Nostro, F.L. Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| topic_facet |
Acetylcholinesterase Acute toxicity Cichlid fish Endosulfan Hematology Histopathology Organochlorine pesticides Teleostei acetylcholinesterase endosulfan cichlid ecotoxicology endosulfan enzyme activity hematology histology histopathology inhibition organochlorine physiology pollution exposure toxicity test acute toxicity anemia animal tissue article Cichlasoma dimerus controlled study environmental exposure enzyme activity female freshwater species histopathology hyperplasia hypertrophy male mean corpuscular hemoglobin mean corpuscular volume mucous cell neurotoxicity nonhuman Perciformes testis injury Animals Cichlids Endosulfan Female Fresh Water Gills Hepatocytes Hydrocarbons, Chlorinated Insecticides Lethal Dose 50 Liver Male Ovary Spleen Testis Water Pollutants, Chemical Cichlasoma Cichlidae Perciformes Teleostei |
| description |
The organochlorine insecticide endosulfan (ES) is widely used despite its high toxicity to fish (96-h LC50 median value of 2.6γgL-1). This study aimed to assess the acute toxicity, histological and physiological parameters after exposure to 0; 0.25; 1; 2; 3; 4 and 16γgL-1 ES for 96h under semi-static conditions in a freshwater perciform fish, Cichlasoma dimerus. Prior to death, fish exhibited behavior indicative of neurotoxicity. No difference was found in brain AChE activity. A decrease in erythrocyte mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration in exposed fish suggests a state of anemia. Histological alterations observed in exposed fish included hyperplasia of the interlamellar epithelium, blood congestion in secondary lamellae, and mucous cells hyperplasia and hypertrophy in gills; pycnotic nuclei and hydropic degeneration in liver; testicular damage. These moderate pathological responses in major organs could become crucial during reproduction and under prolonged exposure periods. © 2011 Elsevier Inc. |
| format |
JOUR |
| author |
Da Cuña, R.H. Rey Vázquez, G. Piol, M.N. Guerrero, N.V. Maggese, M.C. Lo Nostro, F.L. |
| author_facet |
Da Cuña, R.H. Rey Vázquez, G. Piol, M.N. Guerrero, N.V. Maggese, M.C. Lo Nostro, F.L. |
| author_sort |
Da Cuña, R.H. |
| title |
Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| title_short |
Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| title_full |
Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| title_fullStr |
Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| title_full_unstemmed |
Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes) |
| title_sort |
assessment of the acute toxicity of the organochlorine pesticide endosulfan in cichlasoma dimerus (teleostei, perciformes) |
| url |
http://hdl.handle.net/20.500.12110/paper_01476513_v74_n4_p1065_DaCuna |
| work_keys_str_mv |
AT dacunarh assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes AT reyvazquezg assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes AT piolmn assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes AT guerreronv assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes AT maggesemc assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes AT lonostrofl assessmentoftheacutetoxicityoftheorganochlorinepesticideendosulfanincichlasomadimerusteleosteiperciformes |
| _version_ |
1807314473816424448 |