Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives

We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy an...

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Detalles Bibliográficos
Autores principales:	Scorzo, C.M., Fascio, M.L., D'Accorso, N.B., Cabrerab, M.G., Saavedrab, L.A.
Formato:	JOUR
Materias:	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_01035053_v21_n1_p43_Scorzo2023-10-03T14:57:30Z Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives Scorzo, C.M. Fascio, M.L. D'Accorso, N.B. Cabrerab, M.G. Saavedrab, L.A. Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme. © 2010 Sociedade Brasileira de Química. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
spellingShingle	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds Scorzo, C.M. Fascio, M.L. D'Accorso, N.B. Cabrerab, M.G. Saavedrab, L.A. Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
topic_facet	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
description	We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme. © 2010 Sociedade Brasileira de Química.
format	JOUR
author	Scorzo, C.M. Fascio, M.L. D'Accorso, N.B. Cabrerab, M.G. Saavedrab, L.A.
author_facet	Scorzo, C.M. Fascio, M.L. D'Accorso, N.B. Cabrerab, M.G. Saavedrab, L.A.
author_sort	Scorzo, C.M.
title	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_short	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_full	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_fullStr	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_full_unstemmed	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_sort	synthesis and antiacetylcholinesterase activity of new d-glyceraldehyde heterocyclic derivatives
url	http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
work_keys_str_mv	AT scorzocm synthesisandantiacetylcholinesteraseactivityofnewdglyceraldehydeheterocyclicderivatives AT fascioml synthesisandantiacetylcholinesteraseactivityofnewdglyceraldehydeheterocyclicderivatives AT daccorsonb synthesisandantiacetylcholinesteraseactivityofnewdglyceraldehydeheterocyclicderivatives AT cabrerabmg synthesisandantiacetylcholinesteraseactivityofnewdglyceraldehydeheterocyclicderivatives AT saavedrabla synthesisandantiacetylcholinesteraseactivityofnewdglyceraldehydeheterocyclicderivatives
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Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives

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