Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"

This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous...

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Autor principal: Cardinali, D.P.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p247_Cardinali
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spelling todo:paper_00653446_v29_nC_p247_Cardinali2023-10-03T14:52:59Z Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" Cardinali, D.P. axonal transport Melatonin microtubules mitosis secretory process tubulin This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous melatonin release affect tubulin levels in the hypothalamus. Whether all these phenomena are mediated through a common mechanism remains unsettled. © 1981. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p247_Cardinali
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic axonal transport
Melatonin
microtubules
mitosis
secretory process
tubulin
spellingShingle axonal transport
Melatonin
microtubules
mitosis
secretory process
tubulin
Cardinali, D.P.
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
topic_facet axonal transport
Melatonin
microtubules
mitosis
secretory process
tubulin
description This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous melatonin release affect tubulin levels in the hypothalamus. Whether all these phenomena are mediated through a common mechanism remains unsettled. © 1981.
format JOUR
author Cardinali, D.P.
author_facet Cardinali, D.P.
author_sort Cardinali, D.P.
title Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
title_short Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
title_full Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
title_fullStr Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
title_full_unstemmed Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
title_sort molecular biology of melatonin: assessment of the "microtubule hypothesis of melatonin action"
url http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p247_Cardinali
work_keys_str_mv AT cardinalidp molecularbiologyofmelatoninassessmentofthemicrotubulehypothesisofmelatoninaction
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