Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action"
This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous...
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todo:paper_00653446_v29_nC_p247_Cardinali2023-10-03T14:52:59Z Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" Cardinali, D.P. axonal transport Melatonin microtubules mitosis secretory process tubulin This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous melatonin release affect tubulin levels in the hypothalamus. Whether all these phenomena are mediated through a common mechanism remains unsettled. © 1981. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p247_Cardinali |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
axonal transport Melatonin microtubules mitosis secretory process tubulin |
spellingShingle |
axonal transport Melatonin microtubules mitosis secretory process tubulin Cardinali, D.P. Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
topic_facet |
axonal transport Melatonin microtubules mitosis secretory process tubulin |
description |
This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous melatonin release affect tubulin levels in the hypothalamus. Whether all these phenomena are mediated through a common mechanism remains unsettled. © 1981. |
format |
JOUR |
author |
Cardinali, D.P. |
author_facet |
Cardinali, D.P. |
author_sort |
Cardinali, D.P. |
title |
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
title_short |
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
title_full |
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
title_fullStr |
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
title_full_unstemmed |
Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
title_sort |
molecular biology of melatonin: assessment of the "microtubule hypothesis of melatonin action" |
url |
http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p247_Cardinali |
work_keys_str_mv |
AT cardinalidp molecularbiologyofmelatoninassessmentofthemicrotubulehypothesisofmelatoninaction |
_version_ |
1782025351397900288 |