Mild deprotection of steroid esters by Bis(tributyltin)oxide

Bis(tributyltin)oxide (BBTO) has been utilized for the first time for the deprotection of steroid esters. The best results were obtained for 3β-esters, in particular the selective hydrolysis of the 3β-acetyl group in 3β,6α-diacetoxy-5α-pregnan-20-one to give 6α-acetoxy-3β-hydroxy-5α-pregnan-20-one....

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Detalles Bibliográficos
Autores principales: Pérez, M.G., Maier, M.S.
Formato: JOUR
Materias:
6alpha acetoxy 3beta hydroxy 5alpha pregnan 20 one
estrogen
gestagen
unclassified drug
article
hydrolysis
reaction analysis
steroidogenesis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00404039_v36_n19_p3311_Perez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_00404039_v36_n19_p3311_Perez
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spelling todo:paper_00404039_v36_n19_p3311_Perez2023-10-03T14:50:50Z Mild deprotection of steroid esters by Bis(tributyltin)oxide Pérez, M.G. Maier, M.S. 6alpha acetoxy 3beta hydroxy 5alpha pregnan 20 one estrogen gestagen unclassified drug article hydrolysis reaction analysis steroidogenesis Bis(tributyltin)oxide (BBTO) has been utilized for the first time for the deprotection of steroid esters. The best results were obtained for 3β-esters, in particular the selective hydrolysis of the 3β-acetyl group in 3β,6α-diacetoxy-5α-pregnan-20-one to give 6α-acetoxy-3β-hydroxy-5α-pregnan-20-one. © 1995. Fil:Maier, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00404039_v36_n19_p3311_Perez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 6alpha acetoxy 3beta hydroxy 5alpha pregnan 20 one
estrogen
gestagen
unclassified drug
article
hydrolysis
reaction analysis
steroidogenesis
spellingShingle 6alpha acetoxy 3beta hydroxy 5alpha pregnan 20 one
estrogen
gestagen
unclassified drug
article
hydrolysis
reaction analysis
steroidogenesis
Pérez, M.G.
Maier, M.S.
Mild deprotection of steroid esters by Bis(tributyltin)oxide
topic_facet 6alpha acetoxy 3beta hydroxy 5alpha pregnan 20 one
estrogen
gestagen
unclassified drug
article
hydrolysis
reaction analysis
steroidogenesis
description Bis(tributyltin)oxide (BBTO) has been utilized for the first time for the deprotection of steroid esters. The best results were obtained for 3β-esters, in particular the selective hydrolysis of the 3β-acetyl group in 3β,6α-diacetoxy-5α-pregnan-20-one to give 6α-acetoxy-3β-hydroxy-5α-pregnan-20-one. © 1995.
format JOUR
author Pérez, M.G.
Maier, M.S.
author_facet Pérez, M.G.
Maier, M.S.
author_sort Pérez, M.G.
title Mild deprotection of steroid esters by Bis(tributyltin)oxide
title_short Mild deprotection of steroid esters by Bis(tributyltin)oxide
title_full Mild deprotection of steroid esters by Bis(tributyltin)oxide
title_fullStr Mild deprotection of steroid esters by Bis(tributyltin)oxide
title_full_unstemmed Mild deprotection of steroid esters by Bis(tributyltin)oxide
title_sort mild deprotection of steroid esters by bis(tributyltin)oxide
url http://hdl.handle.net/20.500.12110/paper_00404039_v36_n19_p3311_Perez
work_keys_str_mv AT perezmg milddeprotectionofsteroidestersbybistributyltinoxide
AT maierms milddeprotectionofsteroidestersbybistributyltinoxide
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