A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one
The title compound was prepared in 4 steps from 3β-methoxy-21- hydroxy-5α-pregnan-20-one (1). The required intermediate (4) was obtained using lithium enolate derived from t-butyl acetate. Interesting enough, p-tosyl chloride in pyridine quantitatively converted compound 1 into the a-chloro ketone d...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00397911_v23_n8_p1111_Revelli |
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todo:paper_00397911_v23_n8_p1111_Revelli2023-10-03T14:49:55Z A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one Revelli, G.A. Gros, E.G. 4 (3beta methoxy 5alpha androstan 17beta yl) 3 pyrrolin 2 one androstane derivative unclassified drug article drug synthesis nuclear magnetic resonance The title compound was prepared in 4 steps from 3β-methoxy-21- hydroxy-5α-pregnan-20-one (1). The required intermediate (4) was obtained using lithium enolate derived from t-butyl acetate. Interesting enough, p-tosyl chloride in pyridine quantitatively converted compound 1 into the a-chloro ketone derivative (2). © 1993, Taylor & Francis Group, LLC. All rights reserved. Fil:Revelli, G.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00397911_v23_n8_p1111_Revelli |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
4 (3beta methoxy 5alpha androstan 17beta yl) 3 pyrrolin 2 one androstane derivative unclassified drug article drug synthesis nuclear magnetic resonance |
| spellingShingle |
4 (3beta methoxy 5alpha androstan 17beta yl) 3 pyrrolin 2 one androstane derivative unclassified drug article drug synthesis nuclear magnetic resonance Revelli, G.A. Gros, E.G. A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| topic_facet |
4 (3beta methoxy 5alpha androstan 17beta yl) 3 pyrrolin 2 one androstane derivative unclassified drug article drug synthesis nuclear magnetic resonance |
| description |
The title compound was prepared in 4 steps from 3β-methoxy-21- hydroxy-5α-pregnan-20-one (1). The required intermediate (4) was obtained using lithium enolate derived from t-butyl acetate. Interesting enough, p-tosyl chloride in pyridine quantitatively converted compound 1 into the a-chloro ketone derivative (2). © 1993, Taylor & Francis Group, LLC. All rights reserved. |
| format |
JOUR |
| author |
Revelli, G.A. Gros, E.G. |
| author_facet |
Revelli, G.A. Gros, E.G. |
| author_sort |
Revelli, G.A. |
| title |
A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| title_short |
A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| title_full |
A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| title_fullStr |
A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| title_full_unstemmed |
A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| title_sort |
facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| url |
http://hdl.handle.net/20.500.12110/paper_00397911_v23_n8_p1111_Revelli |
| work_keys_str_mv |
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