Synthesis and biological activity of ring-A difluorinated brassinosteroids

In this paper we report the synthesis of four ring-A difluorinated analogs of brassinosteroids. The bioactivity of these new compounds was evaluated using the rice lamina inclination test. The results show that one of these analogs elicits a bioactivity comparable to that of 28-homocastasterone, a h...

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Detalles Bibliográficos
Autores principales: Acebedo, S.L., Alonso, F., Galagovsky, L.R., Ramírez, J.A.
Formato: JOUR
Materias:
Brassinosteroids
Difluorinated steroids
Plant hormones
28 homocastasterone
2alpha, 3alpha difluoro 22,23 dihydroxy 5alpha stigmastan 6 one
2alpha,3alpha difluoro 5alpha stigmast 22 en 6 one
3,3 difluoro 22,23 dihydroxy 5alpha stigmastan 6 one
3,3 difluoro 5alpha stigmast 22 en 6 one
brassinosteroid
unclassified drug
article
biological activity
controlled study
fluorination
receptor binding
synthesis
Cholestanols
Magnetic Resonance Spectroscopy
Molecular Structure
Steroids
Steroids, Heterocyclic
Structure-Activity Relationship
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0039128X_v76_n10-11_p1016_Acebedo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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