Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi
The association between household seroreactivity to Trypanosoma cruzi in dogs and children and T. cruzi infection rates in domestic Triatoma infestons was investigated in 1988-1989 in the rural community of Arnama, north-west Argentina, where house spraying with residual pyrethroids was carried out...
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todo:paper_00359203_v85_n6_p741_Gurtler2023-10-03T14:47:31Z Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi Gürtler, R.E. Cécere, M.C. Rubel, D.N. Petersen, R.M. Schweigmann, N.J. Lauricella, M.A. Bujas, M.A. Segura, E.L. Wisnivesky-Colli, C. argentina article chagas disease dog household infection rate prevalence priority journal risk factor serology triatoma infestans tropical medicine trypanosoma cruzi Adolescent Animal Argentina Chagas Disease Child Disease Reservoirs Dog Diseases Dogs Human Insect Vectors Prevalence Risk Factors Support, Non-U.S. Gov't Triatoma Canis familiaris Triatoma infestans Trypanosoma Trypanosoma cruzi The association between household seroreactivity to Trypanosoma cruzi in dogs and children and T. cruzi infection rates in domestic Triatoma infestons was investigated in 1988-1989 in the rural community of Arnama, north-west Argentina, where house spraying with residual pyrethroids was carried out in 1985. Three years after spraying, a greater reduction of the average T. cruzi prevalence rate in dogs (from 83% to 40%) than in children (from 48% to 30%) was accompanied by a substantial decrease in vector infection rates from 51%-63% to 21%. At a household level, in homes with or without seroreactive children, the percentage of infected T. infestons was 4·5-4·7 times higher when seroreactive dogs were present (27·1%-34·8%) than when they were not (5·8%-7·7%; stratified relative risk [RR] = 4·58). The contribution of seroreactive children to bug infection rates was not significant (RR = 1·29). The combined effect of both seroreactive dogs and seroreactive children fitted equally well with additive or multiplicative transmission models. Bug infection rates showed an increasing trend with the number of seroreactive dogs and an inverse association with the age of the youngest seroreactive dog. Our study supports the hypothesis of a causal association between the presence and number of infected dogs and increased levels of T. cruzi transmission to domestic T. infestons. © 1991. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00359203_v85_n6_p741_Gurtler |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
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R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
argentina article chagas disease dog household infection rate prevalence priority journal risk factor serology triatoma infestans tropical medicine trypanosoma cruzi Adolescent Animal Argentina Chagas Disease Child Disease Reservoirs Dog Diseases Dogs Human Insect Vectors Prevalence Risk Factors Support, Non-U.S. Gov't Triatoma Canis familiaris Triatoma infestans Trypanosoma Trypanosoma cruzi |
| spellingShingle |
argentina article chagas disease dog household infection rate prevalence priority journal risk factor serology triatoma infestans tropical medicine trypanosoma cruzi Adolescent Animal Argentina Chagas Disease Child Disease Reservoirs Dog Diseases Dogs Human Insect Vectors Prevalence Risk Factors Support, Non-U.S. Gov't Triatoma Canis familiaris Triatoma infestans Trypanosoma Trypanosoma cruzi Gürtler, R.E. Cécere, M.C. Rubel, D.N. Petersen, R.M. Schweigmann, N.J. Lauricella, M.A. Bujas, M.A. Segura, E.L. Wisnivesky-Colli, C. Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| topic_facet |
argentina article chagas disease dog household infection rate prevalence priority journal risk factor serology triatoma infestans tropical medicine trypanosoma cruzi Adolescent Animal Argentina Chagas Disease Child Disease Reservoirs Dog Diseases Dogs Human Insect Vectors Prevalence Risk Factors Support, Non-U.S. Gov't Triatoma Canis familiaris Triatoma infestans Trypanosoma Trypanosoma cruzi |
| description |
The association between household seroreactivity to Trypanosoma cruzi in dogs and children and T. cruzi infection rates in domestic Triatoma infestons was investigated in 1988-1989 in the rural community of Arnama, north-west Argentina, where house spraying with residual pyrethroids was carried out in 1985. Three years after spraying, a greater reduction of the average T. cruzi prevalence rate in dogs (from 83% to 40%) than in children (from 48% to 30%) was accompanied by a substantial decrease in vector infection rates from 51%-63% to 21%. At a household level, in homes with or without seroreactive children, the percentage of infected T. infestons was 4·5-4·7 times higher when seroreactive dogs were present (27·1%-34·8%) than when they were not (5·8%-7·7%; stratified relative risk [RR] = 4·58). The contribution of seroreactive children to bug infection rates was not significant (RR = 1·29). The combined effect of both seroreactive dogs and seroreactive children fitted equally well with additive or multiplicative transmission models. Bug infection rates showed an increasing trend with the number of seroreactive dogs and an inverse association with the age of the youngest seroreactive dog. Our study supports the hypothesis of a causal association between the presence and number of infected dogs and increased levels of T. cruzi transmission to domestic T. infestons. © 1991. |
| format |
JOUR |
| author |
Gürtler, R.E. Cécere, M.C. Rubel, D.N. Petersen, R.M. Schweigmann, N.J. Lauricella, M.A. Bujas, M.A. Segura, E.L. Wisnivesky-Colli, C. |
| author_facet |
Gürtler, R.E. Cécere, M.C. Rubel, D.N. Petersen, R.M. Schweigmann, N.J. Lauricella, M.A. Bujas, M.A. Segura, E.L. Wisnivesky-Colli, C. |
| author_sort |
Gürtler, R.E. |
| title |
Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| title_short |
Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| title_full |
Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| title_fullStr |
Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| title_full_unstemmed |
Chagas disease in north-west Argentina: infected dogs as a risk factor for the domestic transmission of Trypanosoma cruzi |
| title_sort |
chagas disease in north-west argentina: infected dogs as a risk factor for the domestic transmission of trypanosoma cruzi |
| url |
http://hdl.handle.net/20.500.12110/paper_00359203_v85_n6_p741_Gurtler |
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