Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1
The antiviral effect of polysaccharides has been known for many years. Carrageenans are considered a good alternative for the prevention of a wide range of diseases, mainly caused by enveloped viruses. The advantages lie on their high availability, low cost and low induction of resistance. The aim o...
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todo:paper_00345288_v98_n_p142_Diogo2023-10-03T14:45:56Z Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 Diogo, J.V. Novo, S.G. González, M.J. Ciancia, M. Bratanich, A.C. Antiviral Herpesvirus Lambda-carrageenan carrageenan lambda carrageenan unclassified drug antivirus agent carrageenan Alphaherpesvirinae animal cell antiviral activity Article Bovine herpesvirus 1 concentration response controlled study drug mechanism Gigartina skottsbergii nonhuman seaweed suid herpesvirus type 1 virus infectivity virus strain animal chemistry dog drug effects MDCK cell line Pseudorabies virus red alga Alphaherpesvirinae Animalia Bovine herpesvirus 1 Gigartina skottsbergii Herpesviridae Human herpesvirus 1 Simplexvirus Suid herpesvirus 1 Animals Antiviral Agents Carrageenan Dogs Herpesvirus 1, Bovine Herpesvirus 1, Suid Madin Darby Canine Kidney Cells Rhodophyta The antiviral effect of polysaccharides has been known for many years. Carrageenans are considered a good alternative for the prevention of a wide range of diseases, mainly caused by enveloped viruses. The advantages lie on their high availability, low cost and low induction of resistance. The aim of this study was to evaluate the sensitivity of two viral pathogens of veterinary interest to the presence of lambda-carrageenan. This is the first report of a lambda-carrageenan having antiviral activity against animal viruses belonging to the Alphaherpesvirinae subfamily, BoHV-1 (bovine herpesvirus type 1) strain Cooper and SuHV-1 (suid herpesvirus type 1) strain Bartha. Lambda-carrageenan was able to reduce infectivity of both viruses with a more pronounced effect against BoHV-1. These results proved, as previously shown for human herpes virus type 1, that these compounds could be used as potential antiviral agents in the veterinary field. © 2014 Elsevier Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00345288_v98_n_p142_Diogo |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antiviral Herpesvirus Lambda-carrageenan carrageenan lambda carrageenan unclassified drug antivirus agent carrageenan Alphaherpesvirinae animal cell antiviral activity Article Bovine herpesvirus 1 concentration response controlled study drug mechanism Gigartina skottsbergii nonhuman seaweed suid herpesvirus type 1 virus infectivity virus strain animal chemistry dog drug effects MDCK cell line Pseudorabies virus red alga Alphaherpesvirinae Animalia Bovine herpesvirus 1 Gigartina skottsbergii Herpesviridae Human herpesvirus 1 Simplexvirus Suid herpesvirus 1 Animals Antiviral Agents Carrageenan Dogs Herpesvirus 1, Bovine Herpesvirus 1, Suid Madin Darby Canine Kidney Cells Rhodophyta |
| spellingShingle |
Antiviral Herpesvirus Lambda-carrageenan carrageenan lambda carrageenan unclassified drug antivirus agent carrageenan Alphaherpesvirinae animal cell antiviral activity Article Bovine herpesvirus 1 concentration response controlled study drug mechanism Gigartina skottsbergii nonhuman seaweed suid herpesvirus type 1 virus infectivity virus strain animal chemistry dog drug effects MDCK cell line Pseudorabies virus red alga Alphaherpesvirinae Animalia Bovine herpesvirus 1 Gigartina skottsbergii Herpesviridae Human herpesvirus 1 Simplexvirus Suid herpesvirus 1 Animals Antiviral Agents Carrageenan Dogs Herpesvirus 1, Bovine Herpesvirus 1, Suid Madin Darby Canine Kidney Cells Rhodophyta Diogo, J.V. Novo, S.G. González, M.J. Ciancia, M. Bratanich, A.C. Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| topic_facet |
Antiviral Herpesvirus Lambda-carrageenan carrageenan lambda carrageenan unclassified drug antivirus agent carrageenan Alphaherpesvirinae animal cell antiviral activity Article Bovine herpesvirus 1 concentration response controlled study drug mechanism Gigartina skottsbergii nonhuman seaweed suid herpesvirus type 1 virus infectivity virus strain animal chemistry dog drug effects MDCK cell line Pseudorabies virus red alga Alphaherpesvirinae Animalia Bovine herpesvirus 1 Gigartina skottsbergii Herpesviridae Human herpesvirus 1 Simplexvirus Suid herpesvirus 1 Animals Antiviral Agents Carrageenan Dogs Herpesvirus 1, Bovine Herpesvirus 1, Suid Madin Darby Canine Kidney Cells Rhodophyta |
| description |
The antiviral effect of polysaccharides has been known for many years. Carrageenans are considered a good alternative for the prevention of a wide range of diseases, mainly caused by enveloped viruses. The advantages lie on their high availability, low cost and low induction of resistance. The aim of this study was to evaluate the sensitivity of two viral pathogens of veterinary interest to the presence of lambda-carrageenan. This is the first report of a lambda-carrageenan having antiviral activity against animal viruses belonging to the Alphaherpesvirinae subfamily, BoHV-1 (bovine herpesvirus type 1) strain Cooper and SuHV-1 (suid herpesvirus type 1) strain Bartha. Lambda-carrageenan was able to reduce infectivity of both viruses with a more pronounced effect against BoHV-1. These results proved, as previously shown for human herpes virus type 1, that these compounds could be used as potential antiviral agents in the veterinary field. © 2014 Elsevier Ltd. |
| format |
JOUR |
| author |
Diogo, J.V. Novo, S.G. González, M.J. Ciancia, M. Bratanich, A.C. |
| author_facet |
Diogo, J.V. Novo, S.G. González, M.J. Ciancia, M. Bratanich, A.C. |
| author_sort |
Diogo, J.V. |
| title |
Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| title_short |
Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| title_full |
Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| title_fullStr |
Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| title_full_unstemmed |
Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 |
| title_sort |
antiviral activity of lambda-carrageenan prepared from red seaweed (gigartina skottsbergii) against bohv-1 and suhv-1 |
| url |
http://hdl.handle.net/20.500.12110/paper_00345288_v98_n_p142_Diogo |
| work_keys_str_mv |
AT diogojv antiviralactivityoflambdacarrageenanpreparedfromredseaweedgigartinaskottsbergiiagainstbohv1andsuhv1 AT novosg antiviralactivityoflambdacarrageenanpreparedfromredseaweedgigartinaskottsbergiiagainstbohv1andsuhv1 AT gonzalezmj antiviralactivityoflambdacarrageenanpreparedfromredseaweedgigartinaskottsbergiiagainstbohv1andsuhv1 AT cianciam antiviralactivityoflambdacarrageenanpreparedfromredseaweedgigartinaskottsbergiiagainstbohv1andsuhv1 AT bratanichac antiviralactivityoflambdacarrageenanpreparedfromredseaweedgigartinaskottsbergiiagainstbohv1andsuhv1 |
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