Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish
Territorial aggression has been widely studied in males and it has been historically suggested that androgens are key mediators of this behavior. However, more recent evidence suggests that it is the aromatization to estrogens, rather than androgens themselves, that is key to regulating this behavio...
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todo:paper_00319384_v194_n_p481_Scaia2023-10-03T14:43:43Z Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish Scaia, M.F. Morandini, L. Noguera, C. Trudeau, V.L. Somoza, G.M. Pandolfi, M. Aggressive behavior Androgens Challenge hypothesis Cichlasoma dimerus Contest Estrogens 11 oxotestosterone estradiol testosterone aggression androgen blood level animal experiment Article cichlid controlled study estradiol blood level estrogen blood level female male nonhuman priority journal social status testosterone blood level Territorial aggression has been widely studied in males and it has been historically suggested that androgens are key mediators of this behavior. However, more recent evidence suggests that it is the aromatization to estrogens, rather than androgens themselves, that is key to regulating this behavior. Females also display aggressive behaviors, but the physiological regulation of female aggression is still understudied when compared to males. In this context, the challenge hypothesis postulates that male-male aggressive interactions stimulate the production of androgens in males in periods of social instability. Here we determine plasma sex steroid levels in Cichlasoma dimerus to assess whether estrogens are related to aggressive behavior and to test the challenge hypothesis in both males and females. We set-up challenge trials as intrasexual dyadic encounters and determined androgen and estrogen levels before and after the trial in both winners and losers. Even though there were no differences in initial estradiol-17β plasma levels between male winners and losers, initial levels were higher (p =.046) in female winners than in losers, while there were no differences in testosterone or 11-ketotestosterone levels. After trials, both males and females showed elevated levels of estradiol-17β and both androgens, but only males exhibited a significant 1.45, 5.42 and 3.2-fold increase in estradiol-17β testosterone and 11-ketotestosterone, respectively (p =.023, p =.016, p =.018). Moreover, changes in circulating levels of estradiol-17β in females after the trials do not depend on their reproductive status or on the outcome of the contest. We suggest that female aggression is associated with initial levels of estradiol-17β and that the challenge hypothesis, originally defined for androgens, could also be extended to estrogens. © 2018 Elsevier Inc. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00319384_v194_n_p481_Scaia |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Aggressive behavior Androgens Challenge hypothesis Cichlasoma dimerus Contest Estrogens 11 oxotestosterone estradiol testosterone aggression androgen blood level animal experiment Article cichlid controlled study estradiol blood level estrogen blood level female male nonhuman priority journal social status testosterone blood level |
| spellingShingle |
Aggressive behavior Androgens Challenge hypothesis Cichlasoma dimerus Contest Estrogens 11 oxotestosterone estradiol testosterone aggression androgen blood level animal experiment Article cichlid controlled study estradiol blood level estrogen blood level female male nonhuman priority journal social status testosterone blood level Scaia, M.F. Morandini, L. Noguera, C. Trudeau, V.L. Somoza, G.M. Pandolfi, M. Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| topic_facet |
Aggressive behavior Androgens Challenge hypothesis Cichlasoma dimerus Contest Estrogens 11 oxotestosterone estradiol testosterone aggression androgen blood level animal experiment Article cichlid controlled study estradiol blood level estrogen blood level female male nonhuman priority journal social status testosterone blood level |
| description |
Territorial aggression has been widely studied in males and it has been historically suggested that androgens are key mediators of this behavior. However, more recent evidence suggests that it is the aromatization to estrogens, rather than androgens themselves, that is key to regulating this behavior. Females also display aggressive behaviors, but the physiological regulation of female aggression is still understudied when compared to males. In this context, the challenge hypothesis postulates that male-male aggressive interactions stimulate the production of androgens in males in periods of social instability. Here we determine plasma sex steroid levels in Cichlasoma dimerus to assess whether estrogens are related to aggressive behavior and to test the challenge hypothesis in both males and females. We set-up challenge trials as intrasexual dyadic encounters and determined androgen and estrogen levels before and after the trial in both winners and losers. Even though there were no differences in initial estradiol-17β plasma levels between male winners and losers, initial levels were higher (p =.046) in female winners than in losers, while there were no differences in testosterone or 11-ketotestosterone levels. After trials, both males and females showed elevated levels of estradiol-17β and both androgens, but only males exhibited a significant 1.45, 5.42 and 3.2-fold increase in estradiol-17β testosterone and 11-ketotestosterone, respectively (p =.023, p =.016, p =.018). Moreover, changes in circulating levels of estradiol-17β in females after the trials do not depend on their reproductive status or on the outcome of the contest. We suggest that female aggression is associated with initial levels of estradiol-17β and that the challenge hypothesis, originally defined for androgens, could also be extended to estrogens. © 2018 Elsevier Inc. |
| format |
JOUR |
| author |
Scaia, M.F. Morandini, L. Noguera, C. Trudeau, V.L. Somoza, G.M. Pandolfi, M. |
| author_facet |
Scaia, M.F. Morandini, L. Noguera, C. Trudeau, V.L. Somoza, G.M. Pandolfi, M. |
| author_sort |
Scaia, M.F. |
| title |
Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| title_short |
Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| title_full |
Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| title_fullStr |
Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| title_full_unstemmed |
Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual aggression in a cichlid fish |
| title_sort |
can estrogens be considered as key elements of the challenge hypothesis? the case of intrasexual aggression in a cichlid fish |
| url |
http://hdl.handle.net/20.500.12110/paper_00319384_v194_n_p481_Scaia |
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