A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns

The contractile reactivity to sympathetic agonists of two different regions of the rat uterus: mesometrial (M) and antimesometrial or lines uteri (LU), was studied. The inhibitory effects of the adrenergic agonists on the spontaneous as well as on the oxytocin-triggered activity were greater in the...

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Autores principales: Sterin-Speziale, N., Gimeno, M.F., Borda, E., Chaud, M., Gimeno, A.L.
Formato: JOUR
Materias:
isoprenaline
noradrenalin
oxytocin
phentolamine
phentolamine mesylate
phenylephrine
sotalol
animal experiment
female genital system
in vitro study
muscle
rat
smooth muscle contraction
uterus contractility
uterus contraction
uterus horn
Animals
Catecholamines
Dose-Response Relationship, Drug
Female
Isoproterenol
Norepinephrine
Oxytocin
Phenylephrine
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Sympatholytics
Uterine Contraction
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00316989_v13_n4_p401_SterinSpeziale
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling todo:paper_00316989_v13_n4_p401_SterinSpeziale2023-10-03T14:41:24Z A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns Sterin-Speziale, N. Gimeno, M.F. Borda, E. Chaud, M. Gimeno, A.L. isoprenaline noradrenalin oxytocin phentolamine phentolamine mesylate phenylephrine sotalol animal experiment female genital system in vitro study muscle rat smooth muscle contraction uterus contractility uterus contraction uterus horn Animals Catecholamines Dose-Response Relationship, Drug Female Isoproterenol Norepinephrine Oxytocin Phenylephrine Rats Rats, Inbred Strains Receptors, Adrenergic Sympatholytics Uterine Contraction The contractile reactivity to sympathetic agonists of two different regions of the rat uterus: mesometrial (M) and antimesometrial or lines uteri (LU), was studied. The inhibitory effects of the adrenergic agonists on the spontaneous as well as on the oxytocin-triggered activity were greater in the M region than in the LU. Beta-adrenoceptor blocking agents abolished the different sensitivity towards the adrenergic agonists between both zones. The results suggest that in the M region there is a higher population of beta adrenoceptors or an augmented affinity of the agonist for them than in the LU. © 1981 The Italian Pharmacological Society. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00316989_v13_n4_p401_SterinSpeziale
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic isoprenaline
noradrenalin
oxytocin
phentolamine
phentolamine mesylate
phenylephrine
sotalol
animal experiment
female genital system
in vitro study
muscle
rat
smooth muscle contraction
uterus contractility
uterus contraction
uterus horn
Animals
Catecholamines
Dose-Response Relationship, Drug
Female
Isoproterenol
Norepinephrine
Oxytocin
Phenylephrine
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Sympatholytics
Uterine Contraction
spellingShingle isoprenaline
noradrenalin
oxytocin
phentolamine
phentolamine mesylate
phenylephrine
sotalol
animal experiment
female genital system
in vitro study
muscle
rat
smooth muscle contraction
uterus contractility
uterus contraction
uterus horn
Animals
Catecholamines
Dose-Response Relationship, Drug
Female
Isoproterenol
Norepinephrine
Oxytocin
Phenylephrine
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Sympatholytics
Uterine Contraction
Sterin-Speziale, N.
Gimeno, M.F.
Borda, E.
Chaud, M.
Gimeno, A.L.
A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
topic_facet isoprenaline
noradrenalin
oxytocin
phentolamine
phentolamine mesylate
phenylephrine
sotalol
animal experiment
female genital system
in vitro study
muscle
rat
smooth muscle contraction
uterus contractility
uterus contraction
uterus horn
Animals
Catecholamines
Dose-Response Relationship, Drug
Female
Isoproterenol
Norepinephrine
Oxytocin
Phenylephrine
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Sympatholytics
Uterine Contraction
description The contractile reactivity to sympathetic agonists of two different regions of the rat uterus: mesometrial (M) and antimesometrial or lines uteri (LU), was studied. The inhibitory effects of the adrenergic agonists on the spontaneous as well as on the oxytocin-triggered activity were greater in the M region than in the LU. Beta-adrenoceptor blocking agents abolished the different sensitivity towards the adrenergic agonists between both zones. The results suggest that in the M region there is a higher population of beta adrenoceptors or an augmented affinity of the agonist for them than in the LU. © 1981 The Italian Pharmacological Society.
format JOUR
author Sterin-Speziale, N.
Gimeno, M.F.
Borda, E.
Chaud, M.
Gimeno, A.L.
author_facet Sterin-Speziale, N.
Gimeno, M.F.
Borda, E.
Chaud, M.
Gimeno, A.L.
author_sort Sterin-Speziale, N.
title A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
title_short A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
title_full A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
title_fullStr A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
title_full_unstemmed A different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
title_sort different contractile response to catecholamines of two regions (mesometrial and antimesometrial) of isolated rat uterine horns
url http://hdl.handle.net/20.500.12110/paper_00316989_v13_n4_p401_SterinSpeziale
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AT bordae adifferentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
AT chaudm adifferentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
AT gimenoal adifferentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
AT sterinspezialen differentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
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AT chaudm differentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
AT gimenoal differentcontractileresponsetocatecholaminesoftworegionsmesometrialandantimesometrialofisolatedratuterinehorns
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