Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro

We have studied the effect of superior spermatic nerve (SSN) section on testicular gonadotropin receptors and in vitro androgen production by immature rat testis. Bilateral testicular denervation had no effect on testicular weight, serum androgens, LH, FSH and PRL levels. Denervation resulted in a s...

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Autores principales:	Campos, M.B., Chiocchio, S.R., Calandra, R.S., Ritta, M.N.
Formato:	JOUR
Materias:	Androgen production Gonadotropin receptors Testicular denervation Testis chorionic gonadotropin follitropin receptor gonadotropin receptor iodine 125 luteinizing hormone receptor membrane receptor androgen blood level androgen synthesis animal cell animal tissue article controlled study denervation follitropin blood level hormone inhibition immaturity isotope labeling luteinizing hormone blood level male nerve transection nonhuman priority journal prolactin blood level radioimmunoassay rat spermatozoon steroidogenesis testis testis development testis weight testosterone blood level
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00283835_v57_n2_p189_Campos
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00283835_v57_n2_p189_Campos
record_format	dspace
spelling	todo:paper_00283835_v57_n2_p189_Campos2023-10-03T14:38:53Z Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro Campos, M.B. Chiocchio, S.R. Calandra, R.S. Ritta, M.N. Androgen production Gonadotropin receptors Testicular denervation Testis chorionic gonadotropin follitropin receptor gonadotropin receptor iodine 125 luteinizing hormone receptor membrane receptor androgen blood level androgen synthesis animal cell animal tissue article controlled study denervation follitropin blood level hormone inhibition immaturity isotope labeling luteinizing hormone blood level male nerve transection nonhuman priority journal prolactin blood level radioimmunoassay rat spermatozoon steroidogenesis testis testis development testis weight testosterone blood level We have studied the effect of superior spermatic nerve (SSN) section on testicular gonadotropin receptors and in vitro androgen production by immature rat testis. Bilateral testicular denervation had no effect on testicular weight, serum androgens, LH, FSH and PRL levels. Denervation resulted in a significant inhibition of hCG stimulated in vitro androgen production. A reduction in the number of testicular LH receptors was observed after SSN section, while FSH binding sites remained unchanged. These results indicate that the number of LH receptors and testicular steroidogenic response to hCG are influenced by nerves reaching the testis. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00283835_v57_n2_p189_Campos
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Androgen production Gonadotropin receptors Testicular denervation Testis chorionic gonadotropin follitropin receptor gonadotropin receptor iodine 125 luteinizing hormone receptor membrane receptor androgen blood level androgen synthesis animal cell animal tissue article controlled study denervation follitropin blood level hormone inhibition immaturity isotope labeling luteinizing hormone blood level male nerve transection nonhuman priority journal prolactin blood level radioimmunoassay rat spermatozoon steroidogenesis testis testis development testis weight testosterone blood level
spellingShingle	Androgen production Gonadotropin receptors Testicular denervation Testis chorionic gonadotropin follitropin receptor gonadotropin receptor iodine 125 luteinizing hormone receptor membrane receptor androgen blood level androgen synthesis animal cell animal tissue article controlled study denervation follitropin blood level hormone inhibition immaturity isotope labeling luteinizing hormone blood level male nerve transection nonhuman priority journal prolactin blood level radioimmunoassay rat spermatozoon steroidogenesis testis testis development testis weight testosterone blood level Campos, M.B. Chiocchio, S.R. Calandra, R.S. Ritta, M.N. Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
topic_facet	Androgen production Gonadotropin receptors Testicular denervation Testis chorionic gonadotropin follitropin receptor gonadotropin receptor iodine 125 luteinizing hormone receptor membrane receptor androgen blood level androgen synthesis animal cell animal tissue article controlled study denervation follitropin blood level hormone inhibition immaturity isotope labeling luteinizing hormone blood level male nerve transection nonhuman priority journal prolactin blood level radioimmunoassay rat spermatozoon steroidogenesis testis testis development testis weight testosterone blood level
description	We have studied the effect of superior spermatic nerve (SSN) section on testicular gonadotropin receptors and in vitro androgen production by immature rat testis. Bilateral testicular denervation had no effect on testicular weight, serum androgens, LH, FSH and PRL levels. Denervation resulted in a significant inhibition of hCG stimulated in vitro androgen production. A reduction in the number of testicular LH receptors was observed after SSN section, while FSH binding sites remained unchanged. These results indicate that the number of LH receptors and testicular steroidogenic response to hCG are influenced by nerves reaching the testis.
format	JOUR
author	Campos, M.B. Chiocchio, S.R. Calandra, R.S. Ritta, M.N.
author_facet	Campos, M.B. Chiocchio, S.R. Calandra, R.S. Ritta, M.N.
author_sort	Campos, M.B.
title	Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
title_short	Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
title_full	Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
title_fullStr	Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
title_full_unstemmed	Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
title_sort	effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
url	http://hdl.handle.net/20.500.12110/paper_00283835_v57_n2_p189_Campos
work_keys_str_mv	AT camposmb effectofbilateraldenervationoftheimmaturerattestisontesticulargonadotropinreceptorsandinvitro AT chiocchiosr effectofbilateraldenervationoftheimmaturerattestisontesticulargonadotropinreceptorsandinvitro AT calandrars effectofbilateraldenervationoftheimmaturerattestisontesticulargonadotropinreceptorsandinvitro AT rittamn effectofbilateraldenervationoftheimmaturerattestisontesticulargonadotropinreceptorsandinvitro
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Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro

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