Reduction in [3H]-corticosterone binding to cytoplasmic receptors in the brain of diabetic rats

The binding of [1, 2, 6, 7-3H]-corticosterone was studied in brain cytosol from normal and streptozotocin-diabetic male rats. The experiments were performed under conditions of incubation time (4h), temperature (0-4°C), time after adrenalectomy (6 days) and corticosterone concentrations (1.2 × 10-8...

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Detalles Bibliográficos
Autores principales: Fridman, O., Foglia, V.G., De Nlcola, A.F.
Formato: JOUR
Materias:
aldosterone
corticosterone
glucocorticoid receptor
steroid receptor
drug receptor
hormone receptor
radioisotope
streptozocin
adrenalectomy
animal
article
binding competition
brain
cytosol
experimental diabetes mellitus
kinetics
male
metabolism
rat
temperature
aldosterone h 3
animal experiment
central nervous system
corticosterone h 3
cytoplasm
diabetes mellitus
endocrine system
Adrenalectomy
Aldosterone
Animal
Binding, Competitive
Brain
Corticosterone
Cytosol
Diabetes Mellitus, Experimental
Kinetics
Male
Rats
Receptors, Glucocorticoid
Receptors, Steroid
Temperature
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00224731_v9_n7_p609_Fridman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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