Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth

The metabolism of [3H]-testosterone in perfused dog adrenals and in adrenal minces of a normal dog has been studied. Three principal metabolites were studied and identified by isotope dilution and gas-liquid chromatography-mass speetrometry: androstenedione, 11β-hydroxyandrostenedione and 11 β-hydro...

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Autores principales: Wassermann, G.F., Baldi, A., del Castillo, E., Charreau, E.
Formato: JOUR
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dog
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00224731_v4_n2_p217_Wassermann
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spelling todo:paper_00224731_v4_n2_p217_Wassermann2023-10-03T14:33:10Z Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth Wassermann, G.F. Baldi, A. del Castillo, E. Charreau, E. androstane derivative androstenedione corticosteroid corticotropin hydroxysteroid oxosteroid testosterone tritium adrenal gland animal article biosynthesis blood crystallization dog drug effect gas chromatography hypophysectomy hypophysis in vitro study male mass spectrometry metabolism perfusion physiology thin layer chromatography Adrenal Cortex Hormones Adrenal Glands Androstenedione Androstenes Animal Chromatography, Gas Chromatography, Thin Layer Corticotropin Crystallization Dogs Hydroxysteroids Hypophysectomy In Vitro Ketosteroids Male Perfusion Pituitary Gland Spectrum Analysis, Mass Testosterone Tritium The metabolism of [3H]-testosterone in perfused dog adrenals and in adrenal minces of a normal dog has been studied. Three principal metabolites were studied and identified by isotope dilution and gas-liquid chromatography-mass speetrometry: androstenedione, 11β-hydroxyandrostenedione and 11 β-hydroxytestosterone. The last of these metabolites is obtained in high yield which is further increased after ACTH administration. © 1973. Fil:Charreau, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00224731_v4_n2_p217_Wassermann
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic androstane derivative
androstenedione
corticosteroid
corticotropin
hydroxysteroid
oxosteroid
testosterone
tritium
adrenal gland
animal
article
biosynthesis
blood
crystallization
dog
drug effect
gas chromatography
hypophysectomy
hypophysis
in vitro study
male
mass spectrometry
metabolism
perfusion
physiology
thin layer chromatography
Adrenal Cortex Hormones
Adrenal Glands
Androstenedione
Androstenes
Animal
Chromatography, Gas
Chromatography, Thin Layer
Corticotropin
Crystallization
Dogs
Hydroxysteroids
Hypophysectomy
In Vitro
Ketosteroids
Male
Perfusion
Pituitary Gland
Spectrum Analysis, Mass
Testosterone
Tritium
spellingShingle androstane derivative
androstenedione
corticosteroid
corticotropin
hydroxysteroid
oxosteroid
testosterone
tritium
adrenal gland
animal
article
biosynthesis
blood
crystallization
dog
drug effect
gas chromatography
hypophysectomy
hypophysis
in vitro study
male
mass spectrometry
metabolism
perfusion
physiology
thin layer chromatography
Adrenal Cortex Hormones
Adrenal Glands
Androstenedione
Androstenes
Animal
Chromatography, Gas
Chromatography, Thin Layer
Corticotropin
Crystallization
Dogs
Hydroxysteroids
Hypophysectomy
In Vitro
Ketosteroids
Male
Perfusion
Pituitary Gland
Spectrum Analysis, Mass
Testosterone
Tritium
Wassermann, G.F.
Baldi, A.
del Castillo, E.
Charreau, E.
Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
topic_facet androstane derivative
androstenedione
corticosteroid
corticotropin
hydroxysteroid
oxosteroid
testosterone
tritium
adrenal gland
animal
article
biosynthesis
blood
crystallization
dog
drug effect
gas chromatography
hypophysectomy
hypophysis
in vitro study
male
mass spectrometry
metabolism
perfusion
physiology
thin layer chromatography
Adrenal Cortex Hormones
Adrenal Glands
Androstenedione
Androstenes
Animal
Chromatography, Gas
Chromatography, Thin Layer
Corticotropin
Crystallization
Dogs
Hydroxysteroids
Hypophysectomy
In Vitro
Ketosteroids
Male
Perfusion
Pituitary Gland
Spectrum Analysis, Mass
Testosterone
Tritium
description The metabolism of [3H]-testosterone in perfused dog adrenals and in adrenal minces of a normal dog has been studied. Three principal metabolites were studied and identified by isotope dilution and gas-liquid chromatography-mass speetrometry: androstenedione, 11β-hydroxyandrostenedione and 11 β-hydroxytestosterone. The last of these metabolites is obtained in high yield which is further increased after ACTH administration. © 1973.
format JOUR
author Wassermann, G.F.
Baldi, A.
del Castillo, E.
Charreau, E.
author_facet Wassermann, G.F.
Baldi, A.
del Castillo, E.
Charreau, E.
author_sort Wassermann, G.F.
title Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
title_short Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
title_full Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
title_fullStr Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
title_full_unstemmed Metabolism of [3H]-testosterone by the adranal of the dog: The action of acth
title_sort metabolism of [3h]-testosterone by the adranal of the dog: the action of acth
url http://hdl.handle.net/20.500.12110/paper_00224731_v4_n2_p217_Wassermann
work_keys_str_mv AT wassermanngf metabolismof3htestosteronebytheadranalofthedogtheactionofacth
AT baldia metabolismof3htestosteronebytheadranalofthedogtheactionofacth
AT delcastilloe metabolismof3htestosteronebytheadranalofthedogtheactionofacth
AT charreaue metabolismof3htestosteronebytheadranalofthedogtheactionofacth
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