Mechanism of disinhibition after brain lesions

Disinhibition syndromes, ranging from mildly inappropriate social behavior to full blown mania, may result from lesions to specific brain areas. Several studies in patients with closed head injuries, brain tumors, stroke lesions, and focal epilepsy have demonstrated a significant association between...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Starkstein, S.E., Robinson, R.G.
Formato: JOUR
Materias:
affect
brain cortex
brain injury
frontal lobe
human
inhibition kinetics
intelligence
mania
short survey
social behavior
temporal lobe
Adult
Animals
Bipolar Disorder
Brain Diseases
Brain Injuries
Cerebral Cortex
Delirium, Dementia, Amnestic, Cognitive Disorders
Female
Frontal Lobe
Functional Laterality
Humans
Inhibition (Psychology)
Male
Neural Pathways
Risk Factors
Temporal Lobe
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00223018_v185_n2_p108_Starkstein
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_00223018_v185_n2_p108_Starkstein
record_format dspace
spelling todo:paper_00223018_v185_n2_p108_Starkstein2023-10-03T14:30:47Z Mechanism of disinhibition after brain lesions Starkstein, S.E. Robinson, R.G. affect brain cortex brain injury frontal lobe human inhibition kinetics intelligence mania short survey social behavior temporal lobe Adult Animals Bipolar Disorder Brain Diseases Brain Injuries Cerebral Cortex Delirium, Dementia, Amnestic, Cognitive Disorders Female Frontal Lobe Functional Laterality Humans Inhibition (Psychology) Male Neural Pathways Risk Factors Temporal Lobe Disinhibition syndromes, ranging from mildly inappropriate social behavior to full blown mania, may result from lesions to specific brain areas. Several studies in patients with closed head injuries, brain tumors, stroke lesions, and focal epilepsy have demonstrated a significant association between disinhibition syndromes and dysfunction of orbitofrontal and basotemporal cortices of the right hemisphere. Based on the phylogenetic origin of these cortical areas and their main connections with dorsal regions related to visuospatial functions, somatosensation, and spatial memory, the orbitofrontal and basotemporal cortices may selectively inhibit or release motor, instinctive, affective, and intellectual behaviors elaborated in the dorsal cortex. Thus, dysfunction of these heteromodal ventral brain areas may result in disinhibited behaviors. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00223018_v185_n2_p108_Starkstein
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic affect
brain cortex
brain injury
frontal lobe
human
inhibition kinetics
intelligence
mania
short survey
social behavior
temporal lobe
Adult
Animals
Bipolar Disorder
Brain Diseases
Brain Injuries
Cerebral Cortex
Delirium, Dementia, Amnestic, Cognitive Disorders
Female
Frontal Lobe
Functional Laterality
Humans
Inhibition (Psychology)
Male
Neural Pathways
Risk Factors
Temporal Lobe
spellingShingle affect
brain cortex
brain injury
frontal lobe
human
inhibition kinetics
intelligence
mania
short survey
social behavior
temporal lobe
Adult
Animals
Bipolar Disorder
Brain Diseases
Brain Injuries
Cerebral Cortex
Delirium, Dementia, Amnestic, Cognitive Disorders
Female
Frontal Lobe
Functional Laterality
Humans
Inhibition (Psychology)
Male
Neural Pathways
Risk Factors
Temporal Lobe
Starkstein, S.E.
Robinson, R.G.
Mechanism of disinhibition after brain lesions
topic_facet affect
brain cortex
brain injury
frontal lobe
human
inhibition kinetics
intelligence
mania
short survey
social behavior
temporal lobe
Adult
Animals
Bipolar Disorder
Brain Diseases
Brain Injuries
Cerebral Cortex
Delirium, Dementia, Amnestic, Cognitive Disorders
Female
Frontal Lobe
Functional Laterality
Humans
Inhibition (Psychology)
Male
Neural Pathways
Risk Factors
Temporal Lobe
description Disinhibition syndromes, ranging from mildly inappropriate social behavior to full blown mania, may result from lesions to specific brain areas. Several studies in patients with closed head injuries, brain tumors, stroke lesions, and focal epilepsy have demonstrated a significant association between disinhibition syndromes and dysfunction of orbitofrontal and basotemporal cortices of the right hemisphere. Based on the phylogenetic origin of these cortical areas and their main connections with dorsal regions related to visuospatial functions, somatosensation, and spatial memory, the orbitofrontal and basotemporal cortices may selectively inhibit or release motor, instinctive, affective, and intellectual behaviors elaborated in the dorsal cortex. Thus, dysfunction of these heteromodal ventral brain areas may result in disinhibited behaviors.
format JOUR
author Starkstein, S.E.
Robinson, R.G.
author_facet Starkstein, S.E.
Robinson, R.G.
author_sort Starkstein, S.E.
title Mechanism of disinhibition after brain lesions
title_short Mechanism of disinhibition after brain lesions
title_full Mechanism of disinhibition after brain lesions
title_fullStr Mechanism of disinhibition after brain lesions
title_full_unstemmed Mechanism of disinhibition after brain lesions
title_sort mechanism of disinhibition after brain lesions
url http://hdl.handle.net/20.500.12110/paper_00223018_v185_n2_p108_Starkstein
work_keys_str_mv AT starksteinse mechanismofdisinhibitionafterbrainlesions
AT robinsonrg mechanismofdisinhibitionafterbrainlesions
_version_ 1807318103843930112

Ejemplares similares