Inflammatory changes after cryosurgery-induced necrosis in human melanoma xenografted in nude mice

There is growing evidence that necrosis, instead of apoptosis, could act as a natural adjuvant, which could activate an immune response. In this work we have investigated if induction of tumor necrosis could trigger the affluence of inflammatory cells at the tumor site, and thus induce an immune res...

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Detalles Bibliográficos
Autores principales:	Gazzaniga, S., Bravo, A., Goldszmid, S.R., Maschi, F., Martinelli, J., Mordoh, J., Wainstok, R.
Formato:	JOUR
Materias:	Cryosurgery Granulocyte-monocyte colony-stimulating factor Inflammatory infiltrate Melanoma liquid nitrogen recombinant granulocyte macrophage colony stimulating factor animal cell animal model antibody response article controlled study cryosurgery cytotoxicity human human cell humoral immunity immune response inflammation inflammatory cell melanoma mouse nonhuman nude mouse priority journal tissue necrosis tumor growth xenograft
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0022202X_v116_n5_p664_Gazzaniga
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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