Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors
Insect repellents are known since many decades ago and constitute a major tool for personal protection against the biting of mosquitoes. Despite their wide use, the understanding of why and how repellents repel is relatively recent. In particular, the question about to what extent insects other than...
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todo:paper_00221910_v81_n_p137_Zermoglio2023-10-03T14:28:23Z Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors Zermoglio, P.F. Martin-Herrou, H. Bignon, Y. Lazzari, C.R. DEET Icaridine Ir40a+ Triatomines Vector insects disease vector hematology infectious disease insect protozoan repellent Hexapoda Rhodnius prolixus diethyltoluamide icaridin insect repellent piperidine piperidine derivative animal animal behavior Chagas disease disease carrier feeding behavior human nymph odor physiology Rhodnius Animals Behavior, Animal Chagas Disease DEET Disease Vectors Feeding Behavior Humans Insect Repellents Nymph Odors Piperidines Rhodnius Smell Insect repellents are known since many decades ago and constitute a major tool for personal protection against the biting of mosquitoes. Despite their wide use, the understanding of why and how repellents repel is relatively recent. In particular, the question about to what extent insects other than mosquitoes are repulsed by repellents remains open. We developed a series of bioassays aimed to test the performance of well established as well as potential repellent molecules on the Chagas disease vector Rhodnius prolixus. Besides testing their ability to prevent biting, we tested the way in which they act, i.e., by obstructing the detection of attractive odours or by themselves. By using three different experimental protocols (host-biting, open-loop orientation to odours and heat-triggered proboscis extension response) we show that DEET repels bugs both in the presence and in the absence of host-associated odours but only at the highest quantities tested. Piperidine was effective with or without a host and icaridine only repelled in the absence of a living host. Three other molecules recently proposed as potential repellents due to their affinity to the Ir40a+ receptor (which is also activated by DEET) did not evoke significant repellency. Our work provides novel experimental tools and sheds light on the mechanism behind repellency in haematophagous bugs. © 2015 Elsevier Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00221910_v81_n_p137_Zermoglio |
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Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
DEET Icaridine Ir40a+ Triatomines Vector insects disease vector hematology infectious disease insect protozoan repellent Hexapoda Rhodnius prolixus diethyltoluamide icaridin insect repellent piperidine piperidine derivative animal animal behavior Chagas disease disease carrier feeding behavior human nymph odor physiology Rhodnius Animals Behavior, Animal Chagas Disease DEET Disease Vectors Feeding Behavior Humans Insect Repellents Nymph Odors Piperidines Rhodnius Smell |
| spellingShingle |
DEET Icaridine Ir40a+ Triatomines Vector insects disease vector hematology infectious disease insect protozoan repellent Hexapoda Rhodnius prolixus diethyltoluamide icaridin insect repellent piperidine piperidine derivative animal animal behavior Chagas disease disease carrier feeding behavior human nymph odor physiology Rhodnius Animals Behavior, Animal Chagas Disease DEET Disease Vectors Feeding Behavior Humans Insect Repellents Nymph Odors Piperidines Rhodnius Smell Zermoglio, P.F. Martin-Herrou, H. Bignon, Y. Lazzari, C.R. Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| topic_facet |
DEET Icaridine Ir40a+ Triatomines Vector insects disease vector hematology infectious disease insect protozoan repellent Hexapoda Rhodnius prolixus diethyltoluamide icaridin insect repellent piperidine piperidine derivative animal animal behavior Chagas disease disease carrier feeding behavior human nymph odor physiology Rhodnius Animals Behavior, Animal Chagas Disease DEET Disease Vectors Feeding Behavior Humans Insect Repellents Nymph Odors Piperidines Rhodnius Smell |
| description |
Insect repellents are known since many decades ago and constitute a major tool for personal protection against the biting of mosquitoes. Despite their wide use, the understanding of why and how repellents repel is relatively recent. In particular, the question about to what extent insects other than mosquitoes are repulsed by repellents remains open. We developed a series of bioassays aimed to test the performance of well established as well as potential repellent molecules on the Chagas disease vector Rhodnius prolixus. Besides testing their ability to prevent biting, we tested the way in which they act, i.e., by obstructing the detection of attractive odours or by themselves. By using three different experimental protocols (host-biting, open-loop orientation to odours and heat-triggered proboscis extension response) we show that DEET repels bugs both in the presence and in the absence of host-associated odours but only at the highest quantities tested. Piperidine was effective with or without a host and icaridine only repelled in the absence of a living host. Three other molecules recently proposed as potential repellents due to their affinity to the Ir40a+ receptor (which is also activated by DEET) did not evoke significant repellency. Our work provides novel experimental tools and sheds light on the mechanism behind repellency in haematophagous bugs. © 2015 Elsevier Ltd. |
| format |
JOUR |
| author |
Zermoglio, P.F. Martin-Herrou, H. Bignon, Y. Lazzari, C.R. |
| author_facet |
Zermoglio, P.F. Martin-Herrou, H. Bignon, Y. Lazzari, C.R. |
| author_sort |
Zermoglio, P.F. |
| title |
Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| title_short |
Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| title_full |
Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| title_fullStr |
Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| title_full_unstemmed |
Rhodnius prolixus smells repellents: Behavioural evidence and test of present and potential compounds inducing repellency in Chagas disease vectors |
| title_sort |
rhodnius prolixus smells repellents: behavioural evidence and test of present and potential compounds inducing repellency in chagas disease vectors |
| url |
http://hdl.handle.net/20.500.12110/paper_00221910_v81_n_p137_Zermoglio |
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