Tracheal remodelling in response to hypoxia

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The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlle...

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Autores principales:	Centanin, L., Gorr, T.A., Wappner, P.
Formato:	JOUR
Materias:	Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00221910_v56_n5_p447_Centanin
record_format	dspace
spelling	todo:paper_00221910_v56_n5_p447_Centanin2023-10-03T14:28:18Z Tracheal remodelling in response to hypoxia Centanin, L. Gorr, T.A. Wappner, P. Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved. Fil:Centanin, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Wappner, P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda
spellingShingle	Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda Centanin, L. Gorr, T.A. Wappner, P. Tracheal remodelling in response to hypoxia
topic_facet	Cell autonomy HIF Hypoxia Plasticity Tracheae embryonic development enzyme hypoxia insect larval development adaptation animal animal anatomy anoxia growth, development and aging histology insect larva physiology review Adaptation, Physiological Animal Structures Animals Anoxia Insects Larva Hexapoda
description	The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved.
format	JOUR
author	Centanin, L. Gorr, T.A. Wappner, P.
author_facet	Centanin, L. Gorr, T.A. Wappner, P.
author_sort	Centanin, L.
title	Tracheal remodelling in response to hypoxia
title_short	Tracheal remodelling in response to hypoxia
title_full	Tracheal remodelling in response to hypoxia
title_fullStr	Tracheal remodelling in response to hypoxia
title_full_unstemmed	Tracheal remodelling in response to hypoxia
title_sort	tracheal remodelling in response to hypoxia
url	http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin
work_keys_str_mv	AT centaninl trachealremodellinginresponsetohypoxia AT gorrta trachealremodellinginresponsetohypoxia AT wappnerp trachealremodellinginresponsetohypoxia
_version_	1807319429668667392

Tracheal remodelling in response to hypoxia

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