Studies on the active centre of rat liver porphyrinogen carboxylyase in vivo effect of hexachlorobenzene

1. 1. Porphyrinogen carboxylyase from the liver of normal and hexachlorobenzene porphyric rats was subjeced to chemical modification using photo-oxidation with methylene blue, diethylpyrocarbonate, butane-2,3-dione, and phenylglyoxal. 2. 2. All of these chemicals inactivated the enzyme from both sou...

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Detalles Bibliográficos
Autores principales: De Catabbi, S.B., De Molina, M.D.C.R., De Viale, L.C.S.M.
Formato: JOUR
Materias:
hexachlorobenzene
uroporphyrinogen decarboxylase
animal experiment
animal tissue
article
controlled study
drug toxicity
enzyme active site
enzyme modification
liver
nonhuman
porphyria
rat
Animal
Arginine
Binding Sites
Carboxy-Lyases
Diethyl Pyrocarbonate
Epoxy Compounds
Female
Hexachlorobenzene
Histidine
Hydroxylamine
Hydroxylamines
Liver
Methylene Blue
Photochemistry
Porphyria
Rats
Rats, Inbred Strains
Spectrophotometry
Support, Non-U.S. Gov't
Uroporphyrinogens
Animalia
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0020711X_v23_n7-8_p675_DeCatabbi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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