A unique family of stable and water-soluble S-nitrosothiol complexes

In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free for...

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Autores principales:	Perissinotti, L.L., Leitus, G., Shimon, L., Estrin, D., Doctorovich, F.
Formato:	JOUR
Materias:	2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00201669_v47_n11_p4723_Perissinotti
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spelling	todo:paper_00201669_v47_n11_p4723_Perissinotti2023-10-03T14:16:59Z A unique family of stable and water-soluble S-nitrosothiol complexes Perissinotti, L.L. Leitus, G. Shimon, L. Estrin, D. Doctorovich, F. 2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free form. Strikingly, in contrast with free S-nitrosothiols, we found that, upon coordination to iridium, they become very stable even in aqueous solutions. The study of these coordinated complexes provides further insight on the elucidation of structural aspects dealing with the nature of the S-N bond in RSNOs, a fact which still remains a matter of controversy. © 2008 American Chemical Society. Fil:Perissinotti, L.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Estrin, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Doctorovich, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water
spellingShingle	2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water Perissinotti, L.L. Leitus, G. Shimon, L. Estrin, D. Doctorovich, F. A unique family of stable and water-soluble S-nitrosothiol complexes
topic_facet	2 thiomalic acid 2-thiomalic acid cysteine ester potassium derivative s nitrosothiol thiomalic acid water article chemistry electrospray mass spectrometry infrared spectroscopy nuclear magnetic resonance spectroscopy solubility ultraviolet spectrophotometry X ray crystallography Crystallography, X-Ray Cysteine Esters Magnetic Resonance Spectroscopy Potassium Compounds S-Nitrosothiols Solubility Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Thiomalates Water
description	In this work, we present a complete and detailed experimental characterization and theoretical study of a variety of coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenyl thiol. Some of them are extremely unstable and sensitive in free form. Strikingly, in contrast with free S-nitrosothiols, we found that, upon coordination to iridium, they become very stable even in aqueous solutions. The study of these coordinated complexes provides further insight on the elucidation of structural aspects dealing with the nature of the S-N bond in RSNOs, a fact which still remains a matter of controversy. © 2008 American Chemical Society.
format	JOUR
author	Perissinotti, L.L. Leitus, G. Shimon, L. Estrin, D. Doctorovich, F.
author_facet	Perissinotti, L.L. Leitus, G. Shimon, L. Estrin, D. Doctorovich, F.
author_sort	Perissinotti, L.L.
title	A unique family of stable and water-soluble S-nitrosothiol complexes
title_short	A unique family of stable and water-soluble S-nitrosothiol complexes
title_full	A unique family of stable and water-soluble S-nitrosothiol complexes
title_fullStr	A unique family of stable and water-soluble S-nitrosothiol complexes
title_full_unstemmed	A unique family of stable and water-soluble S-nitrosothiol complexes
title_sort	unique family of stable and water-soluble s-nitrosothiol complexes
url	http://hdl.handle.net/20.500.12110/paper_00201669_v47_n11_p4723_Perissinotti
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A unique family of stable and water-soluble S-nitrosothiol complexes

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