Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers

Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated ind...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sala, A., Argüelles, C.F., Marino, M.E., Bobillo, C., Fenocchio, A., Corach, D.
Formato: JOUR
Lenguaje:English
Materias:
Autosomal STRs
Mbyá-Guaraní
mtDNA
Native South Amerindian
Y-chromosome STRs
microsatellite DNA
mitochondrial DNA
American Indian
Argentina
article
cell nucleus
female
genetics
human
male
population genetics
Y chromosome
Cell Nucleus
Chromosomes, Human, Y
DNA, Mitochondrial
Female
Genetics, Population
Humans
Indians, North American
Male
Microsatellite Repeats
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated individuals were analyzed. The study involved typing fifteen autosomal STRs, nine Y-chromosome STRs, and four biallele loci in the nonrecombinant region of the Y chromosome, sequencing the mtDNA of hypervariable regions I and II, and detecting the 9-bp ins/del in region V of mtDNA. All autosomal STRs were in Hardy-Weinberg equilibrium. The four major native American mtDNA haplogroups were represented in the sample. Haplogroups A2 and D1 exhibited the highest frequencies (40.5% and 36.0%, respectively), and haplogroups B2 and C1 appeared to be less frequent (17.5% and 6.0%, respectively). The native American haplogroup Q1a3a was observed in a relevant proportion (88.8%). In addition, a nine-STR Y-chromosome haplotype (DYS19*13, DYS389I*14, DYS389II*31, DYS390*24, DYS391*11, DYS392*14, DYS393*11, DYS385A*14, DYS385B*16) exhibited a frequency of more than 36%. Our results indicate that the analyzed Argentinean Guaraní individuals are genetically more closely related to Guaraní from Brazil [genetic distance (.μ)2 = 0.48] than to other related tribes that are geographically closer. Statistical approaches based on autosomal data do not support the hypothesis of genetic drift previously proposed; however, this apparent discrepancy might be due to the lack of sensitivity of the autosomal markers used here. © 2010 Wayne State University Press.

Ejemplares similares