Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers

Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated ind...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sala, A., Argüelles, C.F., Marino, M.E., Bobillo, C., Fenocchio, A., Corach, D.
Formato:	JOUR
Lenguaje:	English
Materias:	Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00187143_v82_n4_p433_Sala
record_format	dspace
spelling	todo:paper_00187143_v82_n4_p433_Sala2023-10-03T14:15:40Z Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers Sala, A. Argüelles, C.F. Marino, M.E. Bobillo, C. Fenocchio, A. Corach, D. Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated individuals were analyzed. The study involved typing fifteen autosomal STRs, nine Y-chromosome STRs, and four biallele loci in the nonrecombinant region of the Y chromosome, sequencing the mtDNA of hypervariable regions I and II, and detecting the 9-bp ins/del in region V of mtDNA. All autosomal STRs were in Hardy-Weinberg equilibrium. The four major native American mtDNA haplogroups were represented in the sample. Haplogroups A2 and D1 exhibited the highest frequencies (40.5% and 36.0%, respectively), and haplogroups B2 and C1 appeared to be less frequent (17.5% and 6.0%, respectively). The native American haplogroup Q1a3a was observed in a relevant proportion (88.8%). In addition, a nine-STR Y-chromosome haplotype (DYS1913, DYS389I14, DYS389II31, DYS39024, DYS39111, DYS39214, DYS39311, DYS385A14, DYS385B*16) exhibited a frequency of more than 36%. Our results indicate that the analyzed Argentinean Guaraní individuals are genetically more closely related to Guaraní from Brazil [genetic distance (.μ)2 = 0.48] than to other related tribes that are geographically closer. Statistical approaches based on autosomal data do not support the hypothesis of genetic drift previously proposed; however, this apparent discrepancy might be due to the lack of sensitivity of the autosomal markers used here. © 2010 Wayne State University Press. Fil:Corach, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR English info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
language	English
orig_language_str_mv	English
topic	Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats
spellingShingle	Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats Sala, A. Argüelles, C.F. Marino, M.E. Bobillo, C. Fenocchio, A. Corach, D. Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
topic_facet	Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats
description	Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated individuals were analyzed. The study involved typing fifteen autosomal STRs, nine Y-chromosome STRs, and four biallele loci in the nonrecombinant region of the Y chromosome, sequencing the mtDNA of hypervariable regions I and II, and detecting the 9-bp ins/del in region V of mtDNA. All autosomal STRs were in Hardy-Weinberg equilibrium. The four major native American mtDNA haplogroups were represented in the sample. Haplogroups A2 and D1 exhibited the highest frequencies (40.5% and 36.0%, respectively), and haplogroups B2 and C1 appeared to be less frequent (17.5% and 6.0%, respectively). The native American haplogroup Q1a3a was observed in a relevant proportion (88.8%). In addition, a nine-STR Y-chromosome haplotype (DYS1913, DYS389I14, DYS389II31, DYS39024, DYS39111, DYS39214, DYS39311, DYS385A14, DYS385B*16) exhibited a frequency of more than 36%. Our results indicate that the analyzed Argentinean Guaraní individuals are genetically more closely related to Guaraní from Brazil [genetic distance (.μ)2 = 0.48] than to other related tribes that are geographically closer. Statistical approaches based on autosomal data do not support the hypothesis of genetic drift previously proposed; however, this apparent discrepancy might be due to the lack of sensitivity of the autosomal markers used here. © 2010 Wayne State University Press.
format	JOUR
author	Sala, A. Argüelles, C.F. Marino, M.E. Bobillo, C. Fenocchio, A. Corach, D.
author_facet	Sala, A. Argüelles, C.F. Marino, M.E. Bobillo, C. Fenocchio, A. Corach, D.
author_sort	Sala, A.
title	Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
title_short	Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
title_full	Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
title_fullStr	Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
title_full_unstemmed	Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
title_sort	genetic analysis of six communities of mbyá-guaraní inhabiting northeastern argentina by means of nuclear and mitochondrial polymorphic markers
url	http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala
work_keys_str_mv	AT salaa geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers AT arguellescf geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers AT marinome geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers AT bobilloc geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers AT fenocchioa geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers AT corachd geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers
_version_	1807320707206479872

Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers

Ejemplares similares