Chiasma interference is blind to centromeres

It has long been assumed, since the early works of Mather, that the centromere plays a central role in chiasma position determination, so much so that in all sequential models chiasma determination was supposed to start or finish at this point. More specifically, it has been assumed that the centrom...

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Autores principales:	Colombo, P.C., Jones, G.H.
Formato:	JOUR
Materias:	Centromere Chiasmata Interference Orthoptera animal article biological model centromere chromosome genetics grasshopper Animals Chromosomes Grasshoppers Models, Genetic Animalia Chorthippus brunneus Leptysma Leptysma argentina
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0018067X_v79_n2_p214_Colombo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_0018067X_v79_n2_p214_Colombo
record_format	dspace
spelling	todo:paper_0018067X_v79_n2_p214_Colombo2023-10-03T14:15:25Z Chiasma interference is blind to centromeres Colombo, P.C. Jones, G.H. Centromere Chiasmata Interference Orthoptera animal article biological model centromere chromosome genetics grasshopper Animals Centromere Chromosomes Grasshoppers Models, Genetic Animalia Chorthippus brunneus Leptysma Leptysma argentina Orthoptera It has long been assumed, since the early works of Mather, that the centromere plays a central role in chiasma position determination, so much so that in all sequential models chiasma determination was supposed to start or finish at this point. More specifically, it has been assumed that the centromere acts as a barrier to the transmission of interference, so that a chiasma in the vicinity of a centromere would not affect the probability of chiasma formation across this point. Some statistical analyses seemed to ratify this supposition. However, a reassessment of the literature led us to the conclusion that the statistical analyses that were not flawed were consistent in showing that interference may act across the centromere. Using large sets of chiasma data from the grasshoppers Leptysma argentina and Chorthippus brunneus and applying statistical approaches that involved either the calculation of coincidence or correlating the distances between the centromere and the nearest chiasma in either arm, it is concluded: 1 that interference acts across the centromere; 2 that the action of interference is not changed by the presence of an intervening centromere. Fil:Colombo, P.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0018067X_v79_n2_p214_Colombo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Centromere Chiasmata Interference Orthoptera animal article biological model centromere chromosome genetics grasshopper Animals Centromere Chromosomes Grasshoppers Models, Genetic Animalia Chorthippus brunneus Leptysma Leptysma argentina Orthoptera
spellingShingle	Centromere Chiasmata Interference Orthoptera animal article biological model centromere chromosome genetics grasshopper Animals Centromere Chromosomes Grasshoppers Models, Genetic Animalia Chorthippus brunneus Leptysma Leptysma argentina Orthoptera Colombo, P.C. Jones, G.H. Chiasma interference is blind to centromeres
topic_facet	Centromere Chiasmata Interference Orthoptera animal article biological model centromere chromosome genetics grasshopper Animals Centromere Chromosomes Grasshoppers Models, Genetic Animalia Chorthippus brunneus Leptysma Leptysma argentina Orthoptera
description	It has long been assumed, since the early works of Mather, that the centromere plays a central role in chiasma position determination, so much so that in all sequential models chiasma determination was supposed to start or finish at this point. More specifically, it has been assumed that the centromere acts as a barrier to the transmission of interference, so that a chiasma in the vicinity of a centromere would not affect the probability of chiasma formation across this point. Some statistical analyses seemed to ratify this supposition. However, a reassessment of the literature led us to the conclusion that the statistical analyses that were not flawed were consistent in showing that interference may act across the centromere. Using large sets of chiasma data from the grasshoppers Leptysma argentina and Chorthippus brunneus and applying statistical approaches that involved either the calculation of coincidence or correlating the distances between the centromere and the nearest chiasma in either arm, it is concluded: 1 that interference acts across the centromere; 2 that the action of interference is not changed by the presence of an intervening centromere.
format	JOUR
author	Colombo, P.C. Jones, G.H.
author_facet	Colombo, P.C. Jones, G.H.
author_sort	Colombo, P.C.
title	Chiasma interference is blind to centromeres
title_short	Chiasma interference is blind to centromeres
title_full	Chiasma interference is blind to centromeres
title_fullStr	Chiasma interference is blind to centromeres
title_full_unstemmed	Chiasma interference is blind to centromeres
title_sort	chiasma interference is blind to centromeres
url	http://hdl.handle.net/20.500.12110/paper_0018067X_v79_n2_p214_Colombo
work_keys_str_mv	AT colombopc chiasmainterferenceisblindtocentromeres AT jonesgh chiasmainterferenceisblindtocentromeres
_version_	1782027026287296512

Chiasma interference is blind to centromeres

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