Characterization of a sexual steroid binding protein in Bufo arenarum

Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is...

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Autores principales: Santa-Coloma, T.A., Fernandez, S., Charreau, E.H.
Formato: JOUR
Materias:
androstanolone
estradiol
metribolone
sex hormone binding protein
testosterone
endocrine system
female genital system
male genital system
methodology
molecular weight
nonhuman
priority journal
sedimentation coefficient
Animal
Bufo arenarum
Electrophoresis, Polyacrylamide Gel
Estradiol
Kinetics
Sex Hormone-Binding Globulin
Stanolone
Substrate Specificity
Testosterone
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00166480_v60_n2_p273_SantaColoma
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_00166480_v60_n2_p273_SantaColoma
record_format dspace
spelling todo:paper_00166480_v60_n2_p273_SantaColoma2023-10-03T14:14:09Z Characterization of a sexual steroid binding protein in Bufo arenarum Santa-Coloma, T.A. Fernandez, S. Charreau, E.H. androstanolone estradiol metribolone sex hormone binding protein testosterone endocrine system female genital system male genital system methodology molecular weight nonhuman priority journal sedimentation coefficient Animal Bufo arenarum Electrophoresis, Polyacrylamide Gel Estradiol Kinetics Sex Hormone-Binding Globulin Stanolone Substrate Specificity Testosterone Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). The physicochemical characterization of SBP indicates a Stokes radius of 43.5 Å, a sedimentation coefficient of 5.2 S, and a molecular weight of 93,300. © 1985. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00166480_v60_n2_p273_SantaColoma
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic androstanolone
estradiol
metribolone
sex hormone binding protein
testosterone
endocrine system
female genital system
male genital system
methodology
molecular weight
nonhuman
priority journal
sedimentation coefficient
Animal
Bufo arenarum
Electrophoresis, Polyacrylamide Gel
Estradiol
Kinetics
Sex Hormone-Binding Globulin
Stanolone
Substrate Specificity
Testosterone
spellingShingle androstanolone
estradiol
metribolone
sex hormone binding protein
testosterone
endocrine system
female genital system
male genital system
methodology
molecular weight
nonhuman
priority journal
sedimentation coefficient
Animal
Bufo arenarum
Electrophoresis, Polyacrylamide Gel
Estradiol
Kinetics
Sex Hormone-Binding Globulin
Stanolone
Substrate Specificity
Testosterone
Santa-Coloma, T.A.
Fernandez, S.
Charreau, E.H.
Characterization of a sexual steroid binding protein in Bufo arenarum
topic_facet androstanolone
estradiol
metribolone
sex hormone binding protein
testosterone
endocrine system
female genital system
male genital system
methodology
molecular weight
nonhuman
priority journal
sedimentation coefficient
Animal
Bufo arenarum
Electrophoresis, Polyacrylamide Gel
Estradiol
Kinetics
Sex Hormone-Binding Globulin
Stanolone
Substrate Specificity
Testosterone
description Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). The physicochemical characterization of SBP indicates a Stokes radius of 43.5 Å, a sedimentation coefficient of 5.2 S, and a molecular weight of 93,300. © 1985.
format JOUR
author Santa-Coloma, T.A.
Fernandez, S.
Charreau, E.H.
author_facet Santa-Coloma, T.A.
Fernandez, S.
Charreau, E.H.
author_sort Santa-Coloma, T.A.
title Characterization of a sexual steroid binding protein in Bufo arenarum
title_short Characterization of a sexual steroid binding protein in Bufo arenarum
title_full Characterization of a sexual steroid binding protein in Bufo arenarum
title_fullStr Characterization of a sexual steroid binding protein in Bufo arenarum
title_full_unstemmed Characterization of a sexual steroid binding protein in Bufo arenarum
title_sort characterization of a sexual steroid binding protein in bufo arenarum
url http://hdl.handle.net/20.500.12110/paper_00166480_v60_n2_p273_SantaColoma
work_keys_str_mv AT santacolomata characterizationofasexualsteroidbindingproteininbufoarenarum
AT fernandezs characterizationofasexualsteroidbindingproteininbufoarenarum
AT charreaueh characterizationofasexualsteroidbindingproteininbufoarenarum
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