Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)

BACKGROUND: Arsenic (As) and its compounds may cause multiple harmful effects on the human organism, interfering with biological processes of vital importance. It is known that the inhabitants of vast areas of the Argentine Republic drink well water contaminated with AS, which results in a disease k...

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Autor principal: Carrica, V.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00146722_v63_n2Suppl_p20_Carrica
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spelling todo:paper_00146722_v63_n2Suppl_p20_Carrica2023-10-03T14:13:18Z Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH) Carrica, V. Argentina arsenic poisoning article carcinoma case report chemically induced disorder chronic disease female human middle aged mouth tumor water pollutant water supply Argentina Arsenic Poisoning Carcinoma Chronic Disease Female Humans Middle Aged Mouth Neoplasms Water Pollutants Water Supply BACKGROUND: Arsenic (As) and its compounds may cause multiple harmful effects on the human organism, interfering with biological processes of vital importance. It is known that the inhabitants of vast areas of the Argentine Republic drink well water contaminated with AS, which results in a disease known as Endemic Regional Chronic Hydroarsenicism (ERCH). It has been observed that these patients present a clinical picture characterized by multiple carcinomatous skin lesions which occur concurrently or successively along long periods of time. PURPOSE: To present the clinical case of a female patient from the arsenical area of Cordoba Province, who had multiple carcinomatous oral lesions. MATERIALS AND METHOD: The patient's history was written and iconographies, surgical excision of the lip lesions, pathological studies of the samples, and evolution observations were done. RESULTS: Based on both the patient's history and follow-up studies, it was possible to prove the presence of multiple successive carcinomatous lesions in the oral mucosa. CONCLUSION: It is concluded that drinking water containing more AS than the quantity accepted by the WHO (0.0 5 ppm) can cause multiple carcinomatous lesions on the oral mucosa as well as on the skin. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00146722_v63_n2Suppl_p20_Carrica
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Argentina
arsenic poisoning
article
carcinoma
case report
chemically induced disorder
chronic disease
female
human
middle aged
mouth tumor
water pollutant
water supply
Argentina
Arsenic Poisoning
Carcinoma
Chronic Disease
Female
Humans
Middle Aged
Mouth Neoplasms
Water Pollutants
Water Supply
spellingShingle Argentina
arsenic poisoning
article
carcinoma
case report
chemically induced disorder
chronic disease
female
human
middle aged
mouth tumor
water pollutant
water supply
Argentina
Arsenic Poisoning
Carcinoma
Chronic Disease
Female
Humans
Middle Aged
Mouth Neoplasms
Water Pollutants
Water Supply
Carrica, V.
Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
topic_facet Argentina
arsenic poisoning
article
carcinoma
case report
chemically induced disorder
chronic disease
female
human
middle aged
mouth tumor
water pollutant
water supply
Argentina
Arsenic Poisoning
Carcinoma
Chronic Disease
Female
Humans
Middle Aged
Mouth Neoplasms
Water Pollutants
Water Supply
description BACKGROUND: Arsenic (As) and its compounds may cause multiple harmful effects on the human organism, interfering with biological processes of vital importance. It is known that the inhabitants of vast areas of the Argentine Republic drink well water contaminated with AS, which results in a disease known as Endemic Regional Chronic Hydroarsenicism (ERCH). It has been observed that these patients present a clinical picture characterized by multiple carcinomatous skin lesions which occur concurrently or successively along long periods of time. PURPOSE: To present the clinical case of a female patient from the arsenical area of Cordoba Province, who had multiple carcinomatous oral lesions. MATERIALS AND METHOD: The patient's history was written and iconographies, surgical excision of the lip lesions, pathological studies of the samples, and evolution observations were done. RESULTS: Based on both the patient's history and follow-up studies, it was possible to prove the presence of multiple successive carcinomatous lesions in the oral mucosa. CONCLUSION: It is concluded that drinking water containing more AS than the quantity accepted by the WHO (0.0 5 ppm) can cause multiple carcinomatous lesions on the oral mucosa as well as on the skin.
format JOUR
author Carrica, V.
author_facet Carrica, V.
author_sort Carrica, V.
title Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
title_short Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
title_full Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
title_fullStr Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
title_full_unstemmed Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (ERCH)
title_sort oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (erch)
url http://hdl.handle.net/20.500.12110/paper_00146722_v63_n2Suppl_p20_Carrica
work_keys_str_mv AT carricav oralmultiplecarcinomatosisinapatientfromanareawithendemicregionalchronichydroarsenicismerch
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