Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids

Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The m...

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Autores principales:	DE LEDERKREMER, R.M., TANAKA, C.T., ALVES, M.J.M., COLLI, W.
Formato:	JOUR
Materias:	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid glucosamine lignoceric acid myristic acid palmitic acid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00142956_v74_n2_p263_DELEDERKREMER
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spelling	todo:paper_00142956_v74_n2_p263_DELEDERKREMER2023-10-03T14:11:57Z Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids DE LEDERKREMER, R.M. TANAKA, C.T. ALVES, M.J.M. COLLI, W. amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The main fatty acids are palmitic (6.9%) and lignoceric (4.6%) acids. Stearic (0.55%), oleic (0.15%) and myristic (0.18%) acids were also found. One third of the fatty acids are bound in the lipopeptidophosphoglycan as esters (14 mmol%) and two thirds as amides (28 mmol%). Lignoceric acid was found to be bound only as amide. Two ninhydrin‐positive compounds, obtained by chloroform extraction of a total acid hydrolysate of the lipopeptidophosphoglycan, were tentatively identified as sphingosine bases. Copyright © 1977, Wiley Blackwell. All rights reserved Fil:DE LEDERKREMER, R.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi
spellingShingle	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi DE LEDERKREMER, R.M. TANAKA, C.T. ALVES, M.J.M. COLLI, W. Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
topic_facet	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi
description	Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The main fatty acids are palmitic (6.9%) and lignoceric (4.6%) acids. Stearic (0.55%), oleic (0.15%) and myristic (0.18%) acids were also found. One third of the fatty acids are bound in the lipopeptidophosphoglycan as esters (14 mmol%) and two thirds as amides (28 mmol%). Lignoceric acid was found to be bound only as amide. Two ninhydrin‐positive compounds, obtained by chloroform extraction of a total acid hydrolysate of the lipopeptidophosphoglycan, were tentatively identified as sphingosine bases. Copyright © 1977, Wiley Blackwell. All rights reserved
format	JOUR
author	DE LEDERKREMER, R.M. TANAKA, C.T. ALVES, M.J.M. COLLI, W.
author_facet	DE LEDERKREMER, R.M. TANAKA, C.T. ALVES, M.J.M. COLLI, W.
author_sort	DE LEDERKREMER, R.M.
title	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_short	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_full	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_fullStr	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_full_unstemmed	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_sort	lipopeptidophosphoglycan from trypanosoma cruzi amide and ester‐linked fatty acids
url	http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
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Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids

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