The initation of glycogen biosynthesis in rat heart
A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of g...
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todo:paper_00142956_v135_n1_p175_BLUMENFELD2023-10-03T14:11:48Z The initation of glycogen biosynthesis in rat heart BLUMENFELD, M.L. WHELAN, W.J. KRISMAN, C.R. glycogen trichloroacetic acid uridine diphosphate glucose animal article biosynthesis heart muscle kinetics metabolism pH precipitation rat rat strain RNA translation solubility Animal Glycogen Hydrogen-Ion Concentration Kinetics Myocardium Peptide Chain Initiation Precipitation Rats Rats, Inbred Strains Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trichloroacetic Acid Uridine Diphosphate Glucose A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of glycogen synthesis occurs by apposition of glucose residues to a protein and that the material so synthesized in vitro corresponds to the protein‐bound glycogen reported to exist in rat heart. The ability to label the putative protein primer in vitro with [14C]glucose should assist the isolation of the primer and the elucidation of the nature of the association between the carbohydrate and protein moeities. Copyright © 1983, Wiley Blackwell. All rights reserved JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00142956_v135_n1_p175_BLUMENFELD |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
glycogen trichloroacetic acid uridine diphosphate glucose animal article biosynthesis heart muscle kinetics metabolism pH precipitation rat rat strain RNA translation solubility Animal Glycogen Hydrogen-Ion Concentration Kinetics Myocardium Peptide Chain Initiation Precipitation Rats Rats, Inbred Strains Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trichloroacetic Acid Uridine Diphosphate Glucose |
spellingShingle |
glycogen trichloroacetic acid uridine diphosphate glucose animal article biosynthesis heart muscle kinetics metabolism pH precipitation rat rat strain RNA translation solubility Animal Glycogen Hydrogen-Ion Concentration Kinetics Myocardium Peptide Chain Initiation Precipitation Rats Rats, Inbred Strains Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trichloroacetic Acid Uridine Diphosphate Glucose BLUMENFELD, M.L. WHELAN, W.J. KRISMAN, C.R. The initation of glycogen biosynthesis in rat heart |
topic_facet |
glycogen trichloroacetic acid uridine diphosphate glucose animal article biosynthesis heart muscle kinetics metabolism pH precipitation rat rat strain RNA translation solubility Animal Glycogen Hydrogen-Ion Concentration Kinetics Myocardium Peptide Chain Initiation Precipitation Rats Rats, Inbred Strains Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trichloroacetic Acid Uridine Diphosphate Glucose |
description |
A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of glycogen synthesis occurs by apposition of glucose residues to a protein and that the material so synthesized in vitro corresponds to the protein‐bound glycogen reported to exist in rat heart. The ability to label the putative protein primer in vitro with [14C]glucose should assist the isolation of the primer and the elucidation of the nature of the association between the carbohydrate and protein moeities. Copyright © 1983, Wiley Blackwell. All rights reserved |
format |
JOUR |
author |
BLUMENFELD, M.L. WHELAN, W.J. KRISMAN, C.R. |
author_facet |
BLUMENFELD, M.L. WHELAN, W.J. KRISMAN, C.R. |
author_sort |
BLUMENFELD, M.L. |
title |
The initation of glycogen biosynthesis in rat heart |
title_short |
The initation of glycogen biosynthesis in rat heart |
title_full |
The initation of glycogen biosynthesis in rat heart |
title_fullStr |
The initation of glycogen biosynthesis in rat heart |
title_full_unstemmed |
The initation of glycogen biosynthesis in rat heart |
title_sort |
initation of glycogen biosynthesis in rat heart |
url |
http://hdl.handle.net/20.500.12110/paper_00142956_v135_n1_p175_BLUMENFELD |
work_keys_str_mv |
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1782023963310817280 |