Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells

Alternative pre-mRNA splicing plays key roles in determining tissue- and species-specific cell differentiation as well as in the onset of hereditary disease and cancer, being controlled by multiple post- and co-transcriptional regulatory mechanisms. We report here that airborne particulate matter, r...

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Detalles Bibliográficos
Autores principales: Buggiano, V., Petrillo, E., Alló, M., Lafaille, C., Redal, M.A., Alghamdi, M.A., Khoder, M.I., Shamy, M., Muñoz, M.J., Kornblihtt, A.R.
Formato: JOUR
Materias:
Air pollution
Alternative splicing
Bone morphogenetic protein
Colon cancer cells
Particulate matter
bone morphogenetic protein
messenger RNA
bone morphogenetic protein 4
particulate matter
primer DNA
RNA precursor
atmospheric pollution
cancer
cytology
industrial waste
protein
RNA
5' untranslated region
air pollution
alternative RNA splicing
Article
cancer cell culture
cancer cell line
cell proliferation
colon cancer
colon carcinogenesis
controlled study
human
human cell
priority journal
transcription elongation
colon tumor
drug effects
genetics
HEK293 cell line
nucleotide sequence
pathology
pharmacology
reverse transcription polymerase chain reaction
tumor cell line
Alternative Splicing
Base Sequence
Bone Morphogenetic Protein 4
Cell Line, Tumor
Colonic Neoplasms
DNA Primers
HEK293 Cells
Humans
Particulate Matter
Reverse Transcriptase Polymerase Chain Reaction
RNA Precursors
RNA, Messenger
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00139351_v140_n_p185_Buggiano
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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