Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides
MALDI-TOF mass spectrometry analyses of several oligosaccharides (aldoses) and oligosaccharide alditols derived from agaroses, kappa- and iota-carrageenans using different matrices (2,5-dihydroxybenzoic acid, nor-harmane, ferulic acid, and the ionic liquid matrices 2,5-dihydroxybenzoic acid-n-butyla...
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todo:paper_00086215_v345_n2_p275_Fatema2023-10-03T14:07:20Z Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides Fatema, M.K. Nonami, H. Ducatti, D.R.B. Gonçalves, A.G. Duarte, M.E.R. Noseda, M.D. Cerezo, A.S. Erra-Balsells, R. Matulewicz, M.C. Agaro-oligosaccharide alditols MALDI MS Agaro-oligosaccharides MALDI MS DHB Iota-carrageenan oligosaccharide alditols MALDI MS Kappa-carrageenan oligosaccharides MALDI MS Nor-harmane Agaro-oligosaccharides Alditols Harmane Iota-carrageenan Kappa carrageenan Kappa-carrageenan oligosaccharides MALDI MS MALDI-MS Nor-harmane Acids Biopolymers Carbohydrates Desorption Ionic liquids Ionization of liquids Ions Mass spectrometers Mass spectrometry Power spectral density Pulse shaping circuits Oligosaccharides agarose alditol aldose carrageenan ferulic acid gentisic acid harman oligosaccharide unclassified drug article carbohydrate analysis chemical bond controlled study desulfation fragmentation reaction hydrolysis matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman priority journal red alga Carrageenan Hydrolysis Indicators and Reagents Oligosaccharides Seaweed Sepharose Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sugar Alcohols MALDI-TOF mass spectrometry analyses of several oligosaccharides (aldoses) and oligosaccharide alditols derived from agaroses, kappa- and iota-carrageenans using different matrices (2,5-dihydroxybenzoic acid, nor-harmane, ferulic acid, and the ionic liquid matrices 2,5-dihydroxybenzoic acid-n-butylamine and ferulic acid-n-butylamine) were conducted. These carbohydrates were selected as model compounds to study the MALDI prompt and post-source decay (PSD) fragmentation processes of both families of oligosaccharides. Sulfated alditols showed in the negative-ion mode the molecular ion as [M-Na]- together with the species yielded by their prompt fragmentation (mainly desulfation) while the sulfated oligosaccharides (aldoses) showed mainly glycosidic prompt fragmentation (glycosidic C-cleavages and desulfation). Non-sulfated aldoses and alditols, which could only be analyzed in positive-ion mode ([M+Na]+), did not suffer any prompt fragmentation. The former yielded cross-ring fragmentation in the PSD mode. Best results were obtained by using 2,5-dihydroxybenzoic acid and/or nor-harmane as matrices for all the compounds studied. © 2009 Elsevier Ltd. All rights reserved. Fil:Noseda, M.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cerezo, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Erra-Balsells, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Matulewicz, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00086215_v345_n2_p275_Fatema |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Agaro-oligosaccharide alditols MALDI MS Agaro-oligosaccharides MALDI MS DHB Iota-carrageenan oligosaccharide alditols MALDI MS Kappa-carrageenan oligosaccharides MALDI MS Nor-harmane Agaro-oligosaccharides Alditols Harmane Iota-carrageenan Kappa carrageenan Kappa-carrageenan oligosaccharides MALDI MS MALDI-MS Nor-harmane Acids Biopolymers Carbohydrates Desorption Ionic liquids Ionization of liquids Ions Mass spectrometers Mass spectrometry Power spectral density Pulse shaping circuits Oligosaccharides agarose alditol aldose carrageenan ferulic acid gentisic acid harman oligosaccharide unclassified drug article carbohydrate analysis chemical bond controlled study desulfation fragmentation reaction hydrolysis matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman priority journal red alga Carrageenan Hydrolysis Indicators and Reagents Oligosaccharides Seaweed Sepharose Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sugar Alcohols |
| spellingShingle |
Agaro-oligosaccharide alditols MALDI MS Agaro-oligosaccharides MALDI MS DHB Iota-carrageenan oligosaccharide alditols MALDI MS Kappa-carrageenan oligosaccharides MALDI MS Nor-harmane Agaro-oligosaccharides Alditols Harmane Iota-carrageenan Kappa carrageenan Kappa-carrageenan oligosaccharides MALDI MS MALDI-MS Nor-harmane Acids Biopolymers Carbohydrates Desorption Ionic liquids Ionization of liquids Ions Mass spectrometers Mass spectrometry Power spectral density Pulse shaping circuits Oligosaccharides agarose alditol aldose carrageenan ferulic acid gentisic acid harman oligosaccharide unclassified drug article carbohydrate analysis chemical bond controlled study desulfation fragmentation reaction hydrolysis matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman priority journal red alga Carrageenan Hydrolysis Indicators and Reagents Oligosaccharides Seaweed Sepharose Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sugar Alcohols Fatema, M.K. Nonami, H. Ducatti, D.R.B. Gonçalves, A.G. Duarte, M.E.R. Noseda, M.D. Cerezo, A.S. Erra-Balsells, R. Matulewicz, M.C. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| topic_facet |
Agaro-oligosaccharide alditols MALDI MS Agaro-oligosaccharides MALDI MS DHB Iota-carrageenan oligosaccharide alditols MALDI MS Kappa-carrageenan oligosaccharides MALDI MS Nor-harmane Agaro-oligosaccharides Alditols Harmane Iota-carrageenan Kappa carrageenan Kappa-carrageenan oligosaccharides MALDI MS MALDI-MS Nor-harmane Acids Biopolymers Carbohydrates Desorption Ionic liquids Ionization of liquids Ions Mass spectrometers Mass spectrometry Power spectral density Pulse shaping circuits Oligosaccharides agarose alditol aldose carrageenan ferulic acid gentisic acid harman oligosaccharide unclassified drug article carbohydrate analysis chemical bond controlled study desulfation fragmentation reaction hydrolysis matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman priority journal red alga Carrageenan Hydrolysis Indicators and Reagents Oligosaccharides Seaweed Sepharose Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sugar Alcohols |
| description |
MALDI-TOF mass spectrometry analyses of several oligosaccharides (aldoses) and oligosaccharide alditols derived from agaroses, kappa- and iota-carrageenans using different matrices (2,5-dihydroxybenzoic acid, nor-harmane, ferulic acid, and the ionic liquid matrices 2,5-dihydroxybenzoic acid-n-butylamine and ferulic acid-n-butylamine) were conducted. These carbohydrates were selected as model compounds to study the MALDI prompt and post-source decay (PSD) fragmentation processes of both families of oligosaccharides. Sulfated alditols showed in the negative-ion mode the molecular ion as [M-Na]- together with the species yielded by their prompt fragmentation (mainly desulfation) while the sulfated oligosaccharides (aldoses) showed mainly glycosidic prompt fragmentation (glycosidic C-cleavages and desulfation). Non-sulfated aldoses and alditols, which could only be analyzed in positive-ion mode ([M+Na]+), did not suffer any prompt fragmentation. The former yielded cross-ring fragmentation in the PSD mode. Best results were obtained by using 2,5-dihydroxybenzoic acid and/or nor-harmane as matrices for all the compounds studied. © 2009 Elsevier Ltd. All rights reserved. |
| format |
JOUR |
| author |
Fatema, M.K. Nonami, H. Ducatti, D.R.B. Gonçalves, A.G. Duarte, M.E.R. Noseda, M.D. Cerezo, A.S. Erra-Balsells, R. Matulewicz, M.C. |
| author_facet |
Fatema, M.K. Nonami, H. Ducatti, D.R.B. Gonçalves, A.G. Duarte, M.E.R. Noseda, M.D. Cerezo, A.S. Erra-Balsells, R. Matulewicz, M.C. |
| author_sort |
Fatema, M.K. |
| title |
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| title_short |
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| title_full |
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| title_fullStr |
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| title_full_unstemmed |
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| title_sort |
matrix-assisted laser desorption/ionization time-of-flight (maldi-tof) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides |
| url |
http://hdl.handle.net/20.500.12110/paper_00086215_v345_n2_p275_Fatema |
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