Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate

O-Sulfation of heparan sulfate was performed in conditions that minimise N-desulfation. NMR spectra and methylation analysis of sulfated heparan sulfate confirmed the selective substitution at O-2 of glucuronic acid units.

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Autores principales: Kovensky, J., Fernández Cirelli, A.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00086215_v303_n1_p119_Kovensky
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spelling todo:paper_00086215_v303_n1_p119_Kovensky2023-10-03T14:06:49Z Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate Kovensky, J. Fernández Cirelli, A. D-Glucuronic acid Heparan sulfate Sulfation glycosaminoglycan heparan sulfate article chemical modification methylation nuclear magnetic resonance spectroscopy priority journal reaction analysis sulfation O-Sulfation of heparan sulfate was performed in conditions that minimise N-desulfation. NMR spectra and methylation analysis of sulfated heparan sulfate confirmed the selective substitution at O-2 of glucuronic acid units. Fil:Kovensky, J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Fernández Cirelli, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00086215_v303_n1_p119_Kovensky
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic D-Glucuronic acid
Heparan sulfate
Sulfation
glycosaminoglycan
heparan sulfate
article
chemical modification
methylation
nuclear magnetic resonance spectroscopy
priority journal
reaction analysis
sulfation
spellingShingle D-Glucuronic acid
Heparan sulfate
Sulfation
glycosaminoglycan
heparan sulfate
article
chemical modification
methylation
nuclear magnetic resonance spectroscopy
priority journal
reaction analysis
sulfation
Kovensky, J.
Fernández Cirelli, A.
Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
topic_facet D-Glucuronic acid
Heparan sulfate
Sulfation
glycosaminoglycan
heparan sulfate
article
chemical modification
methylation
nuclear magnetic resonance spectroscopy
priority journal
reaction analysis
sulfation
description O-Sulfation of heparan sulfate was performed in conditions that minimise N-desulfation. NMR spectra and methylation analysis of sulfated heparan sulfate confirmed the selective substitution at O-2 of glucuronic acid units.
format JOUR
author Kovensky, J.
Fernández Cirelli, A.
author_facet Kovensky, J.
Fernández Cirelli, A.
author_sort Kovensky, J.
title Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
title_short Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
title_full Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
title_fullStr Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
title_full_unstemmed Chemical modification of glycosaminoglycans. Selective 2-sulfation of D-glucuronic acid units in heparan sulfate
title_sort chemical modification of glycosaminoglycans. selective 2-sulfation of d-glucuronic acid units in heparan sulfate
url http://hdl.handle.net/20.500.12110/paper_00086215_v303_n1_p119_Kovensky
work_keys_str_mv AT kovenskyj chemicalmodificationofglycosaminoglycansselective2sulfationofdglucuronicacidunitsinheparansulfate
AT fernandezcirellia chemicalmodificationofglycosaminoglycansselective2sulfationofdglucuronicacidunitsinheparansulfate
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