Phase behavior of freeze-dried phospholipid-cholesterol mixtures stabilized with trehalose

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A study is presented of the role of cholesterol content on the gel-to-liquid crystalline phase transition of freeze-dried liposomes stabilized with trehalose, a well known lyoprotectant. The phospholipids considered in this work, DPPC and DPPE, belong to the two predominant phospholipid species foun...

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Detalles Bibliográficos
Autores principales:	Ohtake, S., Schebor, C., Palecek, S.P., De Pablo, J.J.
Formato:	JOUR
Materias:	Cholesterol DPPC DPPE Freeze-dried Phase transition cholesterol dipalmitoylphosphatidylcholine dipalmitoylphosphatidylethanolamine liposome phospholipid trehalose article enthalpy freeze drying lipid composition lipid membrane phase separation phase transition priority journal temperature sensitivity thermostability 1,2-Dipalmitoylphosphatidylcholine Calorimetry, Differential Scanning Freeze Drying Phosphatidylethanolamines Trehalose Mammalia
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00052736_v1713_n1_p57_Ohtake
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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