Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina
Dogs, the main domestic reservoirs of Trypanosoma cruzi in the Argentine chaco, may be useful as sentinels of vector-mediated transmission of Trypanosoma cruzi in control programmes if canine infections acquired by all other routes could be excluded. In the present study, in the province of Santiago...
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todo:paper_00034983_v92_n6_p671_Castanera2023-10-03T13:56:28Z Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina Castañera, M.B. Lauricella, M.A. Chuit, R. Gürtler, R.E. insecticide Argentina article disease transmission dog multiple regression nonhuman rural area seroconversion serology Triatoma infestans Trypanosoma cruzi trypanosomiasis Animalia Argentina (fish) Canis familiaris Chaco Protozoa Triatoma guasayana Triatoma infestans Trypanosoma Trypanosoma cruzi Villa Dogs, the main domestic reservoirs of Trypanosoma cruzi in the Argentine chaco, may be useful as sentinels of vector-mediated transmission of Trypanosoma cruzi in control programmes if canine infections acquired by all other routes could be excluded. In the present study, in the province of Santiago del Estero, Argentina, the dog populations in the neighbouring villages of Amama, Trinidad, Mercedes, Villa Matilde and Pampa Pozo were studied immediately before spraying of residual insecticides (in 1992 in Amami, Trinidad and Mercedes and 1993-1994 in the other villages) and twice during a subsequent programme of triatomine surveillance (in 1994 and 1996). Overall seropositivity for Trypanosoma cruzi infection (i.e. the proportion of dogs found positive by at least two different serological tests in any one survey) steadily declined from 65% (54/83) in 1992 to 39% (70/182) in 1994 and 15% (36/237) in 1996. No seroconversion was detected between the 1994 and 1996 surveys in any dog aged > 2 years. However, among the dogs aged < 2 years (which were born after virtual elimination of Triatoma infestans from the villages), seropositivity fell from 15% (12/81) in 1994 to 5% (6/131) in 1996. Thirteen demographic, behavioural and entomological variables were analysed by logistic multiple-regression analysis for their association with seropositivity in dogs born locally during the surveillance programme. The total number of Triatoma guasayana collected in the bedroom areas of the owner's house, having a mother which was seropositive for Trypanosama cruzi, and the number of seropositive dogs with which it cohabited were all found to be significant predictors of seropositivity in any dog. The results are the first indication that Triatoma guasayana is the vector responsible for the new cases of Trypanosoma cruzi infection seen in dogs in domestic or peridomestic sites during the surveillance programme. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00034983_v92_n6_p671_Castanera |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
insecticide Argentina article disease transmission dog multiple regression nonhuman rural area seroconversion serology Triatoma infestans Trypanosoma cruzi trypanosomiasis Animalia Argentina (fish) Canis familiaris Chaco Protozoa Triatoma guasayana Triatoma infestans Trypanosoma Trypanosoma cruzi Villa |
| spellingShingle |
insecticide Argentina article disease transmission dog multiple regression nonhuman rural area seroconversion serology Triatoma infestans Trypanosoma cruzi trypanosomiasis Animalia Argentina (fish) Canis familiaris Chaco Protozoa Triatoma guasayana Triatoma infestans Trypanosoma Trypanosoma cruzi Villa Castañera, M.B. Lauricella, M.A. Chuit, R. Gürtler, R.E. Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| topic_facet |
insecticide Argentina article disease transmission dog multiple regression nonhuman rural area seroconversion serology Triatoma infestans Trypanosoma cruzi trypanosomiasis Animalia Argentina (fish) Canis familiaris Chaco Protozoa Triatoma guasayana Triatoma infestans Trypanosoma Trypanosoma cruzi Villa |
| description |
Dogs, the main domestic reservoirs of Trypanosoma cruzi in the Argentine chaco, may be useful as sentinels of vector-mediated transmission of Trypanosoma cruzi in control programmes if canine infections acquired by all other routes could be excluded. In the present study, in the province of Santiago del Estero, Argentina, the dog populations in the neighbouring villages of Amama, Trinidad, Mercedes, Villa Matilde and Pampa Pozo were studied immediately before spraying of residual insecticides (in 1992 in Amami, Trinidad and Mercedes and 1993-1994 in the other villages) and twice during a subsequent programme of triatomine surveillance (in 1994 and 1996). Overall seropositivity for Trypanosoma cruzi infection (i.e. the proportion of dogs found positive by at least two different serological tests in any one survey) steadily declined from 65% (54/83) in 1992 to 39% (70/182) in 1994 and 15% (36/237) in 1996. No seroconversion was detected between the 1994 and 1996 surveys in any dog aged > 2 years. However, among the dogs aged < 2 years (which were born after virtual elimination of Triatoma infestans from the villages), seropositivity fell from 15% (12/81) in 1994 to 5% (6/131) in 1996. Thirteen demographic, behavioural and entomological variables were analysed by logistic multiple-regression analysis for their association with seropositivity in dogs born locally during the surveillance programme. The total number of Triatoma guasayana collected in the bedroom areas of the owner's house, having a mother which was seropositive for Trypanosama cruzi, and the number of seropositive dogs with which it cohabited were all found to be significant predictors of seropositivity in any dog. The results are the first indication that Triatoma guasayana is the vector responsible for the new cases of Trypanosoma cruzi infection seen in dogs in domestic or peridomestic sites during the surveillance programme. |
| format |
JOUR |
| author |
Castañera, M.B. Lauricella, M.A. Chuit, R. Gürtler, R.E. |
| author_facet |
Castañera, M.B. Lauricella, M.A. Chuit, R. Gürtler, R.E. |
| author_sort |
Castañera, M.B. |
| title |
Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| title_short |
Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| title_full |
Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| title_fullStr |
Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| title_full_unstemmed |
Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-western Argentina |
| title_sort |
evaluation of dogs as sentinels of the transmission of trypanosoma cruzi in a rural area of north-western argentina |
| url |
http://hdl.handle.net/20.500.12110/paper_00034983_v92_n6_p671_Castanera |
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