A ruthenium-rhodamine complex as an activatable fluorescent probe

We describe the synthesis and characterization of a ruthenium-bipyridyl complex bearing a rhodamine-based fluorescent ligand. The complex is weakly fluorescent due to the quenching of rhodamine. Upon irradiation of the MLCT band it releases rhodamine in a fast and clean heterolytic reaction, increas...

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Detalles Bibliográficos
Autores principales:	Del Marmol, J., Filevich, O., Etchenique, R.
Formato:	JOUR
Materias:	Flow-injection analysis Fluorescent probes Neuronal markers Planar cavities Synthesis and characterizations Transition metal chemistry Visible light Chelation Fluorescence Fluorophores Ruthenium Synthesis (chemical) Ruthenium compounds
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00032700_v82_n14_p6259_DelMarmol
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00032700_v82_n14_p6259_DelMarmol
record_format	dspace
spelling	todo:paper_00032700_v82_n14_p6259_DelMarmol2023-10-03T13:56:03Z A ruthenium-rhodamine complex as an activatable fluorescent probe Del Marmol, J. Filevich, O. Etchenique, R. Flow-injection analysis Fluorescent probes Neuronal markers Planar cavities Synthesis and characterizations Transition metal chemistry Visible light Chelation Fluorescence Fluorophores Ruthenium Synthesis (chemical) Ruthenium compounds We describe the synthesis and characterization of a ruthenium-bipyridyl complex bearing a rhodamine-based fluorescent ligand. The complex is weakly fluorescent due to the quenching of rhodamine. Upon irradiation of the MLCT band it releases rhodamine in a fast and clean heterolytic reaction, increasing its fluorescence nearly 6-fold and making it the first visible-light activatable fluorophore based in transition metal chemistry. These properties and its lack of toxicity make it a good candidate for its use as a biologically friendly caged fluorescent probe. The use of this probe as a neuronal marker, and as a flow profiler in a thin, planar cavity and in a model flow injection analysis (FIA) is demonstrated. © 2010 American Chemical Society. Fil: Filevich, O. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil: Etchenique, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00032700_v82_n14_p6259_DelMarmol
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Flow-injection analysis Fluorescent probes Neuronal markers Planar cavities Synthesis and characterizations Transition metal chemistry Visible light Chelation Fluorescence Fluorophores Ruthenium Synthesis (chemical) Ruthenium compounds
spellingShingle	Flow-injection analysis Fluorescent probes Neuronal markers Planar cavities Synthesis and characterizations Transition metal chemistry Visible light Chelation Fluorescence Fluorophores Ruthenium Synthesis (chemical) Ruthenium compounds Del Marmol, J. Filevich, O. Etchenique, R. A ruthenium-rhodamine complex as an activatable fluorescent probe
topic_facet	Flow-injection analysis Fluorescent probes Neuronal markers Planar cavities Synthesis and characterizations Transition metal chemistry Visible light Chelation Fluorescence Fluorophores Ruthenium Synthesis (chemical) Ruthenium compounds
description	We describe the synthesis and characterization of a ruthenium-bipyridyl complex bearing a rhodamine-based fluorescent ligand. The complex is weakly fluorescent due to the quenching of rhodamine. Upon irradiation of the MLCT band it releases rhodamine in a fast and clean heterolytic reaction, increasing its fluorescence nearly 6-fold and making it the first visible-light activatable fluorophore based in transition metal chemistry. These properties and its lack of toxicity make it a good candidate for its use as a biologically friendly caged fluorescent probe. The use of this probe as a neuronal marker, and as a flow profiler in a thin, planar cavity and in a model flow injection analysis (FIA) is demonstrated. © 2010 American Chemical Society.
format	JOUR
author	Del Marmol, J. Filevich, O. Etchenique, R.
author_facet	Del Marmol, J. Filevich, O. Etchenique, R.
author_sort	Del Marmol, J.
title	A ruthenium-rhodamine complex as an activatable fluorescent probe
title_short	A ruthenium-rhodamine complex as an activatable fluorescent probe
title_full	A ruthenium-rhodamine complex as an activatable fluorescent probe
title_fullStr	A ruthenium-rhodamine complex as an activatable fluorescent probe
title_full_unstemmed	A ruthenium-rhodamine complex as an activatable fluorescent probe
title_sort	ruthenium-rhodamine complex as an activatable fluorescent probe
url	http://hdl.handle.net/20.500.12110/paper_00032700_v82_n14_p6259_DelMarmol
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A ruthenium-rhodamine complex as an activatable fluorescent probe

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